Writer 2015BBC Date 2017/05/29



Functional dynamics of CLOCK/BMAL1 complex in the mammalian circadian clock

Effect of sumoylation on the function of BMAL1 and Hes6


Studied on bioclock modulator by cell-based assay




Ϲ The roles of Bmal1 in circadian clock regulation

NADP(H) redox state-dependent CLOCK/BMAL1 heterodimer formation and its inhibitory effect on cancer cell growth

Studies on peripheral clocks in adrenal gland and midbrain dopamine neurons


Effect of circadian clockwork on pulsatile gonadotropin-releasing hormone (GnRH) gene expression




Neurometric model of human intelligence using multimodal magnetic resonance images




ھ Regulation on pre-mRNA splicing of GnRH and dopamine receptor systems

Roles of Hairy/Enhancer of Split 6 in Cell Growth and Neuronal Development


In vivo imaging analysis of CLOCK &BMAL1 heterodimerization using bimolecular fluorescence complementation (BiFC)



Transcriptional regulation of StAR gene expression by adrenal peripheral clock machinery

̹ Functional study on sumoylation and ubiquitination of BMAL1 using biomolecular fluorescence complementation (BiFC)

Identification of BMAL1 sumoylation and its implication on circadian clock regulation




ö Functional Studies of the Growth Arrest gene, Gadd45


Ϲ Molecular mechanism underlying the nuclear translocation of CLOCK/BMAL1 heterodimer

Microglia migration toward damaged dopaminergic neurons in the primary mesencephalic culture

ڼȣ Ultradian rhythmicity of gonadotropin-releasing hormone(GnRH) gene expression in the brain slice culture

ȫ Phosphorylation of the CLOCK protein mediates the resetting mechanism of mammalian circadian rhythm

̹̼ Glucocorticoid regulates gonadotropin-releasing hormone (GnRH) pre-mRNA splicing

ѱ Adrenal peripheral clock: circadian rhythm of synthesis and secretion of glucocorticoid




Studies on the mechanism of neural cell death in pentylenetetrazole (GABA-A receptor antagonist)-induced epileptic seizure

ձ Long-lasting influences of maternal stress on the brain functions of adult mice offspring

̼ Neuroendocrine studies on the modulation of the brain estrogen receptor isoforms expression in female rats


A neuroprotective role of coenzyme Q10 in rotenone-mediated dopaminergic cell death in the primary mesencephalic neurons

ڼ Regulation of human Period1 promoter is involved in CREB activation by MAP kinase pathway in human neuroblastoma cells

Possible involvement of TGF- RII in the regulation of nuclear translocation and phosphorylation of BMAL1

Differential adaptive responses to chronic stress of maternally stressed adult mice



Subcellular localization of circadian clock gene produced by recombinant adenoviral expression system

ھ Pre-mRNA splicing of the mouse GnRH: Interactions of 9G8 and SRp30c, two SR proteins

ѱ Modeling ultradian rhythmicity of hypothalamic GnRH neurons




α Gene expression and function in mouse preimplantation embryo development

â Studies on the regulation of hair growth


Studies on the calcium influx mediated by glutamate receptors in SCN2.2 neuronal cells

ڳ Effects of calcium ion on mouse period 1 gene expression in the NIH-3T3 mouse embryonic fibroblast cells

Studies on the genes associated with essential hypertension in korean population

ȣ The involvement of CLOCK:BMAL1 heterodimer in serum-responsive induction of mPer1 expression

Chronic administration of pentylenetetrazole evokes cell death in discrete brain regions of ovariectomized rats




Effect of stress on hypothalamus-pituitary neuroendocrine axis in the female rat.

Studies on the calcium influx mediated by hyperpolarization and ionotropic glutamate receptor in myoblasts

ֿ Roles of protein kinase C isoforms in development and differentiation of GT1 neuronal cells

Studies on the RNA splicing mechanism of the mouse gonadotropin-releasing hormone (GnRH)


Excision of first intron from the gonadotropin-releasing hormone (GnRH)pre-mRNA during postnatal development of normal mice and in adult hypogonadal mice

Effects of calcium ion on human per 1 gene expression in SK-N-SH human neuroblastoma cells

Neuronal differentiation of HiB5 hippocampal progenitor cells by activation of cAMP-dependent protein kinase A

ڰ Interaction of Tra2and SRp30c in GnRH pre-mRNA splicing

̽¾ Modulation of COX-2 expression in rat uterine epithelial cell line, CUE-P by estrogen and progesterone