Publication > SCI 논문 list




222. Kim J, Park I, Jang S, Choi M, Kim D, Sun W, Choe Y, Choi J-W, Moon C, Park SH, Choe HK, Kim K. (2022) Circadian nuclear receptor REV-ERBRa antagonist as a therapy for mood disorders in Parkinson’s disease. Neurotherapeutics. (in press)


221. Kim K. (2022) Special issues on neurobiology: From gene, network to behavior. Mol. Cells. 45(2): 51-52.





220. Kim B, Kim J, Chun M, Park I, Kwak D, Choi M, Kim K, Choe HK. (2021) Multiplex CRISPR-Cas9 system in a single adeno-associated virus to simultaneous knock out redundant clock genes. Sci Rep. 9(4): 9891(1): 2575.




219. Kwon Y-J, Seo E-B, Kwon S-H, Lee S-H, Kim S-K, Park SK, Kim K, Park SG, Park I-C, Park J-W, Ye S-K. (2020) Tumor acidosis promotes metastatic potency via the Bmal1 circadian clock gene in breast cancer. Sci Rep. 9(4): 989.

218. Park I, Kim D, Kim J, Jang S, Choi M, Choe HK, Kim K (2020) microRNA-25 as a novel modulator of circadian Period2 gene oscillation. Exp Mol Med. Sep 23. doi: 10.1038/s12276-020-00496-5.


217. Kwon YJ, Seo EB, Kwon SH, Lee SH, Kim SK, Park SK, Kim K, Park S, Park IC, Park JW, Ye SK (2020) Extracellular acidosis promotes metastatic potency vis decrease of the BMAL1 circadian clock gene in breast cancer. Cells. 9(4): 989. doi: 10.3390/ cells9040989.


216. Yun S, Lee EJ, Choe HK, Son GH, Kim K, Chung S (2020) Programming effects of maternal stress on the circadian system of adult offspring. Exp Mol Med. 52(3): 473-484.


215. Kim D, Choe HK. Kim K (2020) Ultradian rhythms in the hypothalamic arcuate nucleus kisspeptin neurons and developmental processes. Mol Cells. 43(7): 600-606.


214. Ku K, Park I, Kim D, Kim J, Jang S, Choi M, Choe HK, Kim K (2020) Gut microbial metabolites induce changes in circadian oscillation of clock gene expression in the mouse embryonic fibroblast. Mol Cells.43(3): 276-285.


213. Kim D, Jang S, Kim J, Park I, Ku K, Choi M, Lee S, Heo WD, Son GH, Choe HK, Kim K. (2020) Kisspeptin neuron-specific and self-sustained calcium oscillation in the hypothalamic arcuate nucleus of neonatal mice: Regulatory factors of its synchronization. Neuroendocrinology. Jan 15. doi:10.1159/000505922.






212. Lim HR, Vo MT, Kim DJ, Lee UH, Yoon JH, Kim HJ, Kim J, Kim SR, Lee JY, Yang CH, Kim HY, Choi JS, Kim K, Yang E, Kim H, Lee S, Lee BJ, Kim K, Par JW, Ha CM. (2019) DGR2 deficient mice exhibit motor behaviors with reduced strial dopamine release. Intl J Mol Sci. 21(1): 60. doi: 103390/ijms21010060.


211. Lee S, Kim JA, Kim HD, Chung S, Kim K, Choe HK (2019) Real-time temporal dynamics of biocistronic expression mediated by internal ribosome entry site and 2A cleaving sequence. Mol Cells. 42(5): 418-425.


210. Kim SH, Hwang H, Moon DM, Son GH, Kim K, Rhim H. (2019) Physical and functional interaction between 5HT6 receptor and Nova-1. Exp Neurobiol. 28(1): 17-29.

209. Jeong SJ, Lee IY, Jun BO, Ryu YJ, Sohn JW, Kim SP, Woo CW, Koo JW, Cho IJ, Oh U, Kim K, Sun PG. (2019) Korea brain initiative: Emerging issues and institionalization of neuroethics. Neuron. 101(3): 390-393.

208. Kim S-E, Ko I-G, Ji E-S, Ji J-J, Hwang L, Kim S-H, Cho S, Kim C-J, Kim K, Kim K-H. (2019) Treadmill exercise alleviates circadian rhythm disruption-induced memory deficits by activation of glucocorticoid receptor and brain-derived neurotrophic factor-dependent pathway. Intl Neurourol J. 223: S40-49.





207. Sanderson TM, Bradley CA, Georgiou J, Hong YH, Ng AN, Lee Y, Kim H-D, Kim D, Amici M, Son GH, Zhou M, Kim K, Kaang B-K, Kim SJ, Collingridge GL. (2018) The probability of neurotransmitter release governs AMPA receptor trafficking via activity-dependent regulation of mGluR1 surface expression. Cell Rep. 25: 3631-3646.


206. Lee J, Park E, Kim GH, Kwon I, Kim K. (2018) A splicing variant of human Bmal1 acts as a negative regulator of the molecular circadian clock. Exp Mol Med. 50(12): 159.


205. Choi JE, Kim S, Lee J, Kim K, Kaang BK. (2018) Circadian regulation of REV-ERB alpha mediates hippocampal E-LTP in a time-dependent manner. Exp Neurobiol. 27(5): 344-9.

204. Lee, J, Ko YU, Chung Y, Yun N, Kim M, Kim K, Oh YJ. (2018) The acetylation of cyclin-dependent kinase 5 at lysine 33 regulates kinase activity and neurite length in hippocampal neurons. Sci Rep. 8(1): 13676.

203. Son GH, Cha HK, Chung S, Kim K. (2018) Multimodal regulation of circadian glucocorticoid rhythm by central and adrenal clocks. J Endocr Soc. 2(5): 444-59.

202. Kim J, Jang S, Choi M, Chung S, Choe Y, Kyoung Choe H, Son GH, Rhee K, Kim K. (2018) Abrogation of the circadian nuclear receptor REV-ERB alpha exacerbates 6-hydroxydopamine-induced dopaminergic neurodegeneration. Mol Cells. 41(8): 742-52.


201. Jang J, Chung S, Choi Y, Lim HY, Son Y, Chun SK, Son GH, Kim K, Suh YG, Jung JW (2018) The cryptochrome inhibitor KS15 enhances E-box-mediated transcription feedback action of a circadian transcription-repressor complex. Life Sci. 200: 49-55.





200. Kim J, Jang S, Choe HK, Chung S, Son GH, Kim K. (2017) Implication of circadian rhythm in dopamine and mood regulation. Mol Cells 140(7): 50-456.

199. Cho B, Cho HM, Jo Y, Kim HD, Song M, Moon C, Kim H, Kim K, Sesaki H, Rhyu IJ, Kim H, Sun W. (2017) Constriction of the mitochondrial inner compartment is a priming event for mitochondrial division. Nat Commun. 8: 15754.


198. Chung S, Lee EJ, Cha HK, Kim J, Kim D, Song GH, Kim K (2017) Cooperative role of the suprachiasmatic nucleus central clock and the adrenal clock in controlling circadian glucocorticoid rhythm. Sci Rep. 7: 46404.


197. Vo MT, Ko MS, Lee UH, Yoon EH, Lee BJ, Cho WJ, Ha CM, Kim K, Park JW (2017) Developmentally regulated GTP-binding protein 2 depletion leads to mitochondrial dysfunction through downregulation of dynamin-related protein1. Biochem Biophys Res Commun. 486(4): 1014-1020.




196. Jeong SJ, Lee H, Hur EM, Choe Y, Koo JW, Rah JC, Lee KJ, Lim HH, Sun W, Moon C, Kim K (2016) Korea brain initiative: Integration and control of brain functions. Neuron 92:607-11.

195. Son GH, Chung S, Ramirez VD, Kim K (2016) Pharmacological modulators of molecular clock and their therapeutic potentials in circadian rhythm-related diseases. Med Chem (Los Angeles). 6:724-733.

194. Hwang JY, Lee J, Oh CK, Kang HW, Hwang IY, Um JW, Park HC, Kim S, Shin JH, Park WY, Darnell RB, Um HD, Chung KC, Kim K, Oh YJ (2016) Proteolytic degradation and potential role of onconeural protein cdr2 in neurodegeneration. Cell Death Dis. 7(6):e2240.


193. Jeong B, Hong JH, Kim H, Choe HK, Kim K, Lee KJ (2016) Multi-stability of circadian phase wave within early postnatal suprachiasmatic nucleus. Sci Rep. 6: 21463.


192. Lee J, Lee S, Chung S, Park N, Son GH, An H, Jang J, Chang DJ, Suh YG, Kim K (2016) Identification of a novel circadian clock modulator controlling BMAL1 expression through ROR/REV-ERB-response element-dependent mechanism. Biochem Biophys Res Commun. 469(3): 580-6.


191. Row H, Jeong J, Cho S, Kim S, Kim K (2016) HL271, a novel chemical compound derived from metformin, differs from metformin in its effects on the circadian clock and metabolism. Biochem Biophys Res Commun. 469(3): 783-9.

190. Lee J, Ko HG, Kim K, Kaang BK. (2016) Mildly increased mechanical nociceptive sensitivity in REV-ERB alpha knock-out mice. Exp Neurobiol. 25(6): 342-346





189. Park N, Kim HD, Cheon S, Row H, Lee J, Han DH, Cho S, Kim K (2015) A novel Bmal1 mouse reveals essential roles of the C-terminal domain on circadian rhythms. PLos One. e0138661.

188. Chun SK, Chung S, Kim HD, Lee JH, Jang J, Km J, Kim D, Son GH, Oh YJ, Suh YG, Lee CS, Kim K (2015) A synthetic cryptochrome inhibitor induces anti-proliferative effects and increases chemosensitivity in human breast cancer cells. Biochem Biopys Res Commun. 467(2): 441-6.


187. Lee Y, Chun SK, Kim K (2015) Sumoylation controls CLOCK-BMAL1-mediated clock resetting via CBP recruitment in nuclear transcriptional foci. Biochim Biopys Acta. 1853: 2697-2708.


186. Song H, Moon M, Choe HK, Jang C, Kim A, Cho S, Kim K, Mook-Jung I (2015) Ab-induced degradation of BMAL1 and CBP leads to circadian rhythm disruption in Alzeimer’s disease. Mol Neurodegener. 19:10-13.


185. Choe HK, Chun SK, Kim J, Kim D, Kim HD, Kim K (2015) Real-time GnRH transcription of GnRH promoter-driven luciferase-expressing transgenic mice: Effect of kisspeptin. Neuroendocrinology. 102(3): 194-9.

184. Lee J, Chun SK, Son GH, Kim K, (2015) Sumoylation of Hes6 regulates protein degradation and Hes1-mediated transcription. Edocrinol Metab. 30(3) 381-8

183. Koo J, Che HK, Kim HD, Son GH, Kim K, (2015) Effect of mefloquine, a gap junction blocker on circadian period2 gene oscillation in the mouse suprachiasmatic nucleus ex vivo. Endocrinol Metab. 30(3) 361-70





182. Chung S, Lee EJ, Yun S, Choe HK, Park SB, Son HJ, Kim KS, Dluzen DE, Lee I, Hwang O, Son GH, Kim K (2014) Impact of circadian nuclear receptor REV-ERBa midbrain dopamine production and mood regulation. Cell. 157(4): 858-68.


181. Nam HJ, Boo K, Kim D, Han DH, Choe HK, Kim CR, Sun W, Kim H, Kim K, Lee H, Metzger E, Schuele R, Yoo SH, Takahashi JS, Cho S, Son GH, BaeK SH. (2014) Phosphorylation of LSD1 by PKCa is crucial for circadian rhythmicity and phase resetting. Molecular Cell. 53(5): 791-805.


180. Chun SK, Jang J, Chung S, Yun H, Kim NJ, Jung JW, Son GH, Kim K (2014) Identification and validation of cryptochrome inhibitors that modulate the molecular circadian clock. ACS Chem Biol. 9(5): 1213.

179. Kim DK, Yun S, Son GH, Hwang JI, Park CR, Kim JI, Kim K, Vaudry H, Seong JY. (2014) Coevolution of the spexin/galanin/kisspeptin family: Spexin activates galanin receptor type II and III. Endocrinology. 155(5): 1864-73.

178. Han DH, Lee YJ, Kim K, Kim CJ, Cho S. (2014) Modulation of glucocorticoid receptor induction properties by core circadian clock proteins. Mol Cell Endocrinol. 383(1-2): 170-80.

177. Noh JY, Han DH, Kim MH, Ko IG, Kim SE, Park N, Choe HK, Kim KH, Kim K, Kim CJ, Cho S. (2014) Presence of multiple circadian oscillators in the tissues controlling voiding function in mice. Exp Mol Med. 46:e81. doi:10.1038/emm.2013.153


176. Park I, Lee Y, Kim HD, Kim K (2014) Effect of resveratrol, a SIRT1 activator on the interactions of the CLOCK/BMAL1 complex. Endocrinol Metab. 29(3): 379-87.





175. Whitehead G, Jo J, Hogg EL, Piers T, Kim DH, Seaton G, Seok H, Bru-Mercier G, Son GH, Regan P, Hilderbrandt L, Waite E, Kim BC, Kerrigan TL, Kim K, Whitcomb DL, Collingridge GL, Lightman SL, Cho K. (2013) Acute stress causes rapid synaptic insertion of Ca2+-permeable AMPA receptors to facilitate long-term potentiation in the hippocampus. Brain. 136(Pt12): 3753-65.


174. Lee S, Song B, Kim J, Park K, Hong I, An B, Song S, Lee J, Park S, Kim J, Park D, Lee CJ, Kim K, Shin KS, Tsien RW, Choi S. (2013) GluA1 phosphorylation at serine 831 in the lateral amygdala is required for fear renewal. Nature Neurosci. 16(10): 1436-44.


173. Moon Y, Kim JY, Kim WR, Kim HJ, Jang MJ, Nam Y, Kim K, Kim H, Sun W. (2013) Function of ezrin-radixin-moesin proteins in migration of subventricular zone-derived neuroblasts following traumatic brain injury. Stem Cells. 31(8): 1696-705.

172. Son H, Jeong HS, Cho M, Lee J, Lee H, Yoon K, Jeong AY, Jung S, Kim K, Cheon DS. (2013) Seroepidemiology of predominant norvirus strains circulating in Korea by using recombinant virus-like particle antigens. Foodborne Path Dis. 10(5): 461-6.


171. Cheon S, Park N, Cho S, Kim K. (2013) Glucocorticoid-mediated Period2 induction delays the phase of circadian rhythm. Nucleic Acid Res. 41(12): 6161-74.

170. Choe HK, Kim HD, Park SH, Lee HW, Park JY, Seong JY, LIghtman SL, Son GH, Kim K. (2013) Synchronous activation of gonadotropin-releasing hormone gene transcription and secretion by pulsatile kisspeptin stimulation. Proc Natl Acad Sci USA. 110(14):5677-82.


169. Hwang JI, Moon MJ, Park S, Kim DK, Cho EB, Ha N, Son GH, Kim K, Vaudry H, Seong JY (2013) Expansion of secretin-like G protein-coupled receptors and their ligands via local duplications before and after two rounds of whole-genome duplication. Mol Biol Evol. 30(5):1119-30.





168. Choi EW, Seen DS, Song YB, Son HS, Jung NC, Huh WK, Hahn JS, Kim K, Jeong JY, Lee TG (2012) AdHTS: a high-throughput system for generating recombinant adenvirus. J Biotechnology. .162:246-52.


167. Yoon JA, Han DH, Noh JY, Kim MH, Son GH, Kim K, Kim CJ, Pak YK, Cho S. (2011) Meal time shift disturbs circadian rhythmicity along with metabolic and behavioral alterations in mice. PLos One. Aug. 7(8): e44053


166. Kim H, Park JH, Kim K. (2012) Lipid-like components released from degenerating dopaminergic neurons trigger the dynamic migration of microglia. BBRC. 426: 18-25.


165. Park N, Cheon S, Son GH, Cho S, Kim K (2012) Chronic circadian disturbance by a shortened light-dark cycle increases mortality. Neurobiol Aging. .33(6):1122 e11-22.

164. Moon MJ, Kim HY, Park S, Kim DK, Cho EB, Park CR, You DJ, Hwang JI, Kim K, Choe H, Seong JY (2012) Evolutionary conserved residues at the GLP-1 receptor core confer ligand-induced receptor activation. J Biol Chem. 287: 3873-84.





163. Kim TW, Moon Y, Kim K, Lee JE, Koh HC, Rhyu IJ, Kim H, Sun W. (2011) Dissociation of progressive dopaminergic neuronal death and behavioral impairments by Bax deletion in a mouse model of Parkinson’s disease. PLoS One. Nov.21 6(10):e25346

162. Son GH, Chung S. Kim K (2011) The adrenal peripheral clock: Glucocorticoid and the circadian timing system. Front Neuroendocrinol. 32(4): 451-65.


161. Park E, Iaccarino C, Lee J, Kwon I, Baik SM, Kim M, Seong JY, Son GH, Borrelli E, Kim K (2011) Regulatory roles of hnRNP M and Nova-1 in the alternative splicing of the dopamine D2 receptor pre-mRNA. J Biol Chem. 28: 25301-8

160. Lee EJ, Son GH, Chung S, Lee S, Kim J, Choi S, Kim K (2011) Impairment of fear memory consolidation in maternally stressed male offspring: evidence for nongenomic glucocorticoid action on the amygdale. J Neurosci. 21:7131-40.


159. Kim HD, Choe HK, Chung S, Kim M, Seong JY, Son GH, Kim K (2011) Class-C SOX transcription factor control GnRH gene expression via the intronic transcriptional enhancer. Mol. Endocrinol. 25: 304-8.

158. Moon Y, Kim JY, Choi SY, Kim K, Kim H, Sun W. (2011) Induction of ezrin-radjxin-moesin molecules after cryogenic traumatic brain injury of the mouse cortex. Neuroreport. 22:304-8.


157. Eun B, Kim HJ, Kim SY, Kim TW, Hong ST, Choi KM, Shim JK, Moon Y, Kim K, Kim H, Sun W. (2011) Induction of Per1 expression following an experimentally induced epilepsy in the mouse hippocampus. Neurosci. Lett. 498: 110-3.

156. Chung S, Son GH, Kim K. (2011) Adrenal peripheral oscillator in generating the circadian glucocorticoid rhythm. Ann N Y Acad Sci. 1220:71-81.

155. Chung S, Son GH, Kim K. (2011) Circadian rhythm of adrenal glucocorticoid: Its regulation and clinical implications. Biochem Biophys Acta. 1812:581-91.

154. Choe HK, Son GH, Chung S, Kim M, Sun W, Kim H, GEUM D, Kim K. (2011) Maternal stress retards fetal development in mice with transcriptome-wide impact on gene expression profiles of the limb. Stress. 14:194-204.

153. Kim CH, Leung A, Huh YH, Ynag E, Kim DJ, Leblanc P, Ryu H, Kim K, Kim DW, Garland EM, Raj SR, Biaggioni I, Robertson D, Kim KS (2011) Norepinephrine deficiency is caused by combined abnormal mRNA processing and defective protein trafficking of dopamine beta-hydroxylase. J Biol Chem. 286:9196-9204.

152. Kwon I, Choe HK, Son GH, Kim K. (2011) Mammalian molecular clocks. Exp Neurobiol. 20:18-28.

151. Son GH, Chung S, Kim K (2011) Biological rhythms and neuroendocrine systems. Endocrinol Metab. 25(4):249-57.





150. Moon Y, Choi SY, Kim K, Kim H, Sun W. (2010) Expression of connexin29 and 32 in the penumbra region after traumatic brain injury of mice. Neuroreport. 21:1135-9.


149. Lee Y, Lee J, Kwon I, Nakajima Y, Ohmiya Y, Son GH, Lee KH, Kim K. (2010) Coactivation of the CLOCK-BMAL1 complex by CBP mediates resetting of the circadian clock. J Cell Sci. 123:3547-57.


148. Eun B, Cho B, Moon Y, Kim SY, Kim K, Kim H, Sun W. (2010) Induction of neuronal apoptosis by expression of Hes6 via p53-dependent pathway. Brain Res. 1313:1-8.



147. Oda A, Katayose Y, Yabuuchi S, Yamamoto K, Mizuma M, Shirasou S, Onogawa T, Ohtsuka H, Yoshida H, Hayashi H, Rikiyama T, Kim H, Choe Y, Kim K, Son H, Motoi F, Egawa S, Unno M. (2009) Clock gene mouse period2 overexpression inhibits growth of human pancreatic cancer cells and has synergistic effect with cisplatin. Anticancer Res. 29(4):1201-9.


146. Park E, Lee MS, Baik SM, Cho EB, Son GH, Seong JY, Lee KH, Kim K (2009) Nova-1 mediates glucocorticoid-induced inhibition of pre-mRNA splicing of gonadotropin-releasing hormone transcripts. J Biol Chem. 284(19): 12792-800.


145. Kim DK, Yang JS, Maiti K, Hwang JI, Kim K, Seen D, Ahn Y, Lee C, Kang BC, Kwon HB, Cheon J., and Seong JY. (2009) A gonadotropin-releasing hormone-II antagonist induces autophagy of prostate cancer cells. Cancer Res. 69(3): 923-31.


144. Lee YR, Tsunekawa K, Moon MJ, Um HN, Hwang JI, Osugi T, Otaki N, Sunakawa Y, Kim K, Vaudry H, Kwon HB, Seong JY, and Tsutsui K (2009) Molecular evolution of multiple forms of kisspeptin and GRP54 receptors in vertebrates. Endocrinology. I150(6): 2837-46.




143. Son GH, Chung S, Choe HK, Kim HD, Baik SM, Lee H, Lee HW, Choi S, Sun W, Kim H, Cho S, Lee KH, Kim K (2008) Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production. Proc. Natl Acad Sci USA.105: 20970-5.


142. Choi YY, Shamosh NA, Cho SH, DeYoung CG, Lee MJ, Lee JM, Kim SI, Cho ZH, Kim K, Gray JR, Lee KH (2008) Multiple bases of human intelligence revealed by cortical thickness and neural activation. J Neurosci. 28: 10323-9.


141. Lee J, Lee Y, Lee MJ, Park E, Kang SW, Chung CH, Lee KH, Kim K (2008) Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of CLOCK/BMAL1 complex. Mol Cell Biol. 28: 6056-65.


140. Oh DY, Yoon JM, Moon MJ, Hwang JI, Choe H, Lee JY, Kim JI, Kim S, Rhim H, O'Dell DK, Walker JM, Na HS, Lee MG, Kwon HB, Kim K, Seong JY (2008) Identification of Farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92. J Biol Chem. 283: 21054-64.


139. Eun B, Lee Y, Hong S, Kim J, Lee HW, Kim K, Sun W, Kim H (2008) Hes6 controls cell proliferation via interaction with CREB binding protein in the PML nuclear body. J Biol Chem. 283:5939-49.




138. Kim J, Lee S, Park K, Hong I, Song B, Son G, Park H, Kim WR, Park E, Choe HK, Kim H, Lee C, Sun W, Kim K, Shin KS, Choi S (2007) Amygdala depotentiation and fear extinction. Proc Natl Acad Sci USA. 104:20955-60.


137. Kim WR, Kim Y, Eun B, Park OH, Kim H, Kim K, Park CH, Vinsant S, Oppenheim RW, Sun W (2007) Impaired migration in the rostral migratory stream but spared olfactory function after the elimination of programmed cell death in Bax knock-out mice. J Neurosci. 27:14392-403.


136. Shim HS, Kim H, Lee J, Son GH, Cho S, Oh TH, Kang SH, Seen DS, Lee KH, Kim K (2007) Rapid activation of CLOCK by Ca2+-dependent protein kinase C mediates resetting of the mammalian circadian clock. EMBO Rep. 8:366-71.


135. S on GH, Chung S, Geum D, Kang SS, Choi WS, Kim K, Choi S (2007) Hyperactivity and alteration of the midbrain dopaminergic system in maternally stressed male mice offspring. Biochem Biophys Res Commun. 352:823-9.




134. Lee KH, Choi YY, Gray JR, Cho SH, Chae JH, Lee S, Kim K (2006) Neural correlates of superior intelligence: Stronger recruitment of posterior parietal cortex. Neuroimage. 29:578-86.


133. Park E, Han J, Son GH, Lee MS, Chung S, Park SH, Park K, Lee KH, Choi S, Seong JY, Kim K (2006) Cooperative actions of Tra2alpha with 9G8 and SRp30c in the RNA splicing of the gonadotropin-releasing hormone (GnRH) gene transcript. J Biol Chem. 281:401-9.


132. Son GH, Geum D, Chung S, Kim EJ, Jo JH, Kim CM, Lee KH, Kim H, Choi S, Kim HT, Lee CJ, Kim K (2006) Maternal stress produces learning deficits associated with impairment of NMDA receptor-mediated synaptic plasticity. J Neurosci. 26:3309-18.


131. Park JH, Cho H, Kim H, Kim K (2006) Repeated brief epileptic seizures by pentylenetetrazole cause neurodegeneration and promote neurogenesis in discrete brain regions of freely moving adult rats. Neuroscience. 140:673-84.


130. Kim HS, Yumkham S, Choi JH, Son GH, Kim K, Ryu SH, Suh PG (2006) Serotonin stimulates GnRH secretion through the c-Src-PLC gamma1 pathway in GT1-7 hypothalamic cells. J Endocrinol. 190:581-91.


129. Kwon I, Lee J, Chang SH, Jung NC, Lee BJ, Son GH, Kim K, Lee KH (2006) BMAL1 shuttling controls transactivation and degradation of the CLOCK/BMAL1 heterodimer. Mol Cell Biol. 26:7318-30.


128. Jung SR, Kim K, Hille B, Nguyen TD, Koh DS (2006) Pattern of Ca2+ increase determines the type of secretory mechanism activated in dog pancreatic duct epithelial cells. J Physiol. 576:163-78.


127. Choi SY, Kim DK, Eun B, Kim K, Sun W, Kim H (2006) Anti-apoptotic function of thymosin-beta in developing chick spinal motoneurons. Biochem Biophys Res Commun. 346:872-8.


126. Oh DY, Kim K, Kwon HB, Seong JY (2006) Cellular and molecular biology of orphan G protein-coupled receptors. Intl Rev Cytol. 252:163-218.




125. Moon Y, Lee KH, Park JH, Geum D, Kim K (2005) Mitochondrial membrane depolarization and the selective death of dopaminergic neurons by rotenone: protective effect of coenzyme Q10. J Neurochem. 93:1199-208.


124. Oh DY, Song JA, Moon MJ, Kim JI, Kim K, Kwon HB, Seong JY (2005) Membrane-proximal region of the carboxyl terminus of the gonadotropin-releasing hormone receptor (GnRHR) confers differential signal transduction between mammalian and nonmammalian GnRHRs. Mol Endocrinol. 19:722-31.


123. Khang I, Sonn S, Park JH, Rhee K, Park D, Kim K (2005) Expression of epithin in mouse preimplantation development: the functional role in compaction. Dev Biol. 281:134-44.


122. Son GH, Park E, Jung H, Han J, Lee KH, Seong JY, Kim K (2005) GnRH pre-mRNA splicing: Solving the mystery of a nature’s knockout, hpg mouse. Biochem Biophys Res Commun. 326:261-7.


121. Park CE, Cha KY, Kim K, Lee KA (2005) Expression of cell cycle regulatory genes during primordial-primary follicle transition in the mouse ovary. Fertil Steril. 83:410-8.


120. Li JH, Choe H, Wang AF, Maiti K, Wang C, Salam A, Chun SY, Lee WK, Kim K, Kwon HB, Seong JY (2005) Extracellular loop 3 (EL3) and EL3-proximal transmembrane helix 7 of the mammalian type I and type II gonadotropin-releasing hormone (GnRH) receptors determine differential ligand selectivity to GnRH-I and GnRH-II. Mol Pharmcol. 67:1099-110.


119. Chung S, Son GH, Park SH, Park E, Lee KH, Geum D, Kim K (2005) Differential adaptive responses to chronic stress of maternally stressed male mice offspring. Endocrinology. 146:3202-10.


118. Li JH, Sicard F, Salam MA, Baek M, LePrince J, Vaudry H, Kim K, Kwon HB, Seong JY (2005) Molecular cloning and functional characterization of a type-I neurotensin receptor (NTR) and a novel NTR from the bullfrog brain. J Mol Endocrinol. 34:793-807.


117. Maiti K, Oh DY, Moon JS, Acharjee S, Li JH, Bai DG, Park HS, Lee K, Lee YC, Jung NC, Kim K, Vaudry H, Kwon HB, Seong JY (2005) Differential effects of gonadotropin-releasing hormone (GnRH)-I and GnRH-II on prostate cancer cell signaling and death. J Clin Endocrinol Metab. 90:4287-98.


116. Lee JS, Zhang MH, Yun EK, Geum D, Kim K, Kim TH, Lim YS, Seo JS (2005) Heat shock protein 27 interacts with vimentin and prevents in-solubilization of vimentin subunits induced by cadmium. Exp Mol Med. 37:427-35.


115. Son GH, Geum D, Chung S, Park E, Lee KH, Choi S, Kim K (2005) A protective role of 27-kDa heat shock protein in glucocorticoid-evoked apoptotic cell death of hippocampal progenitor cells. Biochem Biophys Res Commun. 338:1751-8.




114. Lee KH, Park JY, Kim K (2004) NMDA receptor-mediated calcium influx plays an essential role in myoblast fusion. FEBS Lett. 578:47-52.


113. Yoo JC, Chang JR, Kim SH, Jang SK, Wolgemuth DJ, Kim K, Rhee K (2004) NIP1/XB51/NECAB3 is a potential substrate of Nek2, suggesting specific roles of Nek2 in Golgi. Exp Cell Res. 292:393-402.


112. Lee J, Hong J, Kim E, Kim K, Kim SW, Krishnamurthy H, Chung SS, Wolgemuth DJ, Rhee K (2004) Developmental stage-specific expression of Rbm suggests its involvement in early phases of spermatogenesis. Mol Hum Reprod. 10:259-64.


111. Sonn S, Khang I, Kim K, Rhee K (2004) Suppression of Nek2A in mouse early embryos confirms its requirement for chromosome segregation. J Cell Sci. 117: 5557-66.


110. Park CE, Shin MR, Jeon EH, Cha KY, Lee SH, Kim K, Kim NH, Lee KA (2004) Oocyte-selective expression of MT transposon-like element, clone MTi7 and its role in oocyte maturation and embryo development. Mol Reprod Dev. 69:365-74.


109. Achrjee S, Do-Rego JC, Oh DY, Ahn RS, Choe H, Vaudry H, Kim K, Seong JY, Kwon HB (2004) Identification of amino acid residues that direct differential ligand selectivity of mammalian and nonmammalian V1a type receptors for arginine vasopressin and vasotocin. Insights into molecular coevolution of V1a type receptors and their ligands. J Biol Chem. 279:54445-53.


108. Wang C, Yun O, Maiti K, Oh DY, Kim K, Chae CH, Lee CJ, Seong JY, Kwon HB (2004) Position of Pro and Ser near Glu7.32 in the extracellular loop 3 of mammalian and nonmammalian gonadotropin-releasing hormone (GnRH) receptors is a critical determinant for differential ligand selectivity of mammalian GnRH and chicken GnRH-II. Mol Endocrinol. 18:105-16.


107. Kim J, Choe Y, Son GH, Park J-H, Lee S, Khang I, Lee CC, Lee KH, Kim K (2004) Calcium-induced expression of periods 1 in SK-N-SH human neuroblastoma cells. Exp Neurobiol. 13: 39-46.


106. Han K, Lee S, Park J, Son GH, Khang I, Lee KH, Lee CC, Kim K (2004) Modeling ultradian rhythmicity of the hypothalamic GnRH neurosecretory cells. Exp Neurobiol. 13: 47-56.



105. Seong JY, Wang L, Oh DY, Yun O, Maiti K, Li JH, Soh JM, Choi HS, Kim K, Vaudry H, Kwon HB (2003) Ala/Thr(201) in extracellular loop 2 and Leu/Phe(290) in transmembrane domain 6 of type 1 frog gonadotropin-releasing hormone receptor confer differential ligand sensitivity and signal transduction. Endocrinology. 144:454-66.


104. Jung H, Choe Y, Kim H, Park N, Son GH, Khang I, Kim K (2003) Involvement of CLOCK:BMAL1 heterodimer in serum-responsive mPer1 induction. Neuroreport. 14:15-9.


103. Lee S, Lee SA, Shim C, Khang I, Lee KA, Park YM, Kang BM, Kim K (2003) Identification of estrogen-regulated genes in the mouse uterus using a delayed implantation model. Mol Reprod Dev. 64:405-13.


102. Choe Y, Jung H, Khang I, Kim K (2003) Selective roles of protein kinase C isoforms on cell migration of immortalized hypothalamic neurons. J Neuroendocrinol. 15:508-15.


101. Son GH, Jung H, Seong JY, Choe Y, Geum D, Kim K (2003) Excision of the first intron from the gonadotropin-releasing hormone (GnRH) transcript serves as a key regulatory step for GnRH biosynthesis. J Biol Chem. 278:18037-44.


100. Choe Y, Son GH, Lee S, Park E, Moon Y, Kim K (2003) Cell differentiation of GnRH neurons and alternative RNA splicing of GnRH gene transcript. Neuro- endocrinology 77:282-90.




99. Kim M, Geum D, Khang I, Park YM, Kang BM, Lee KA, Kim K (2002) Expression pattern of HSP25 in mouse preimplantation embryo: heat shock responses during oocyte maturation. Mol Reprod Dev. 61:3-13.


98. Kim CD, Choe Y, Shim C, Kim K (2002) Interferon beta secreted from human hair dermal papillar cells inhibits the growth of outer root sheath cells cultured in vitro. Biochem Biophys Res Commun. 290:1133-8.


97. Park JY, Lee D, Maeng JU, Koh DS, Kim K (2002) Hyperpolarization, but not depolarization, increases intracellular Ca(2+) level in cultured chick myoblasts. Biochem Biophys Res Commun. 290:1176-82.


96. Geum D, Son GH, Kim K (2002) Phosphorylation-dependent cellular localization and thermoprotective role of hsp25 in hippocampal HiB5 cells. J Biol Chem. 277:19913-21.


95. Kim MS, Hur MK, Son YJ, Park JI, Chun SY, D'Elia AV, Damante G, Cho S, Kim K, Lee BJ (2002) Regulation of pituitary adenylate cyclase- activating polypeptide gene transcription by TTF-1, a homeodomain-containing transcription factor. J Biol Chem. 277:36863-71.


94. Han J, Son GH, Seong JY, Kim K (2002) GnRH pre-mRNA splicing: role of exonic splicing enhancer. Prog Brain Res. 141:209-19.


93. Seong JY, Han J, Park S, Wuttke W, Jarry H, Kim K (2002) Exonic splicing enhancer-dependent splicing of the gonadotropin-releasing hormone premessenger ribonucleic acid is mediated by tra2alpha, a 40 kilodalton serine-arginine-rich(SR) protein. Mol Endocrinol. 16:2426-38.


92. Dluzen D, Park JH, Kim K (2002) Modulation of olfactory bulb tyrosine hydroxylase and catecholamine transporter mRNA by estrogen. Mol Brain Res. 108:121-8.


91. Kim G. Choe Y, Park J, Cho S, Kim K (2002) Activation of protein kinase A pathway induces neuronal differentiation of HiB5 hippocampal progenitor cells. Mol Brain Res. 109:134-45.


90. Kim H, Ha CM, Choi J, Choi EJ, Jeon J, Kim C, Park SK, Kang SS, Kim K, Lee BJ (2002) Ontogeny and the possible function of a novel epidermal growth factor-like repeat domain-containing protein, NELL2, in the rat brain. J Neurochem. 83:1389-400.


89. Choe Y, Lee BJ, Kim K (2002) Participation of protein kinase C alpha isoform and extracellular signal-regulated kinase in neurite outgrowth of GT1 hypothalamic neurons. J Neurochem. 83:1412-22.




88. Han J, Seong JY, Kim K, Wuttke W, Jarry H (2001) Analysis of exonic splicing enhancers in the mouse gonadotropin-releasing hormone (GnRH) gene. Mol Cell Endocrinol. 173:157-66.


87. Cho S, Chung JJ, Choi Y, Choi HS, Han Kim D, Rhee K, Kim K (2001) A functional retinoic acid response element (RARE) is present within the distal promoter sequence of the rat gonadotropin-releasing hormone (GnRH) gene. Mol Brain Res. 87:204-13.


86. Cho S, Chung J, Han J, Ju Lee B, Han Kim D, Rhee K, Kim K (2001) 9-cis-Retinoic acid represses transcription of the gonadotropin-releasing hormone (GnRH) gene via proximal promoter region that is distinct from all-trans-retinoic acid response element. Mol Brain Res. 87:214-22.


85. Sun W, Lee H, Choe Y, Cho S, Kim DH, Kim K (2001) Evidence for direct involvement of beta-catenin in phorbol ester-induced neurite outgrowth in GT1-1 hypothalamic neurons. J Neuroendocrinol. 13:249-60.


84. Park S, Seong JY, Son GH, Kang SS, Lee S, Kim SR, Kim K (2001) Analysis of steroid-induced genes in the rat preoptic area-anterior hypothalamus using a differential-display reverse transcriptase-polymerase chain reaction. J Neuro- endocrinol. 13:531-9.


83. Seong JY, Kim BW, Park S, Son GH, Kim K (2001) First intron excision of GnRH pre-mRNA during postnatal development of normal mice and adult hypogonadal mice. Endocrinology 142:4454-61.


82. Son GH, Geum D, Jung H, Kim K (2001) Glucocorticoid inhibits growth factor-induced differentiation of hippocampal progenitor HiB5 cells. J Neurochem. 79:1013-21.


81. Choi EJ, Ha CM, Choi J, Kang SS, Choi WS, ParkSK,Kim K, Lee BJ (2001) Low-density cDNA array-coupled to PCR differential display identifies new estrogen-responsive genes during the postnatal differentiation of the rat hypothalamus. Mol Brain Res. 97:115-28.




80. Kang SS, Kim SR, Leonhardt S, Jarry H, Wuttke W, Kim K (2000) Effect of interleukin-1 on gonadotropin-releasing hormone (GnRH) and GnRH receptor gene expression in castrated male rats. J Neuroendocrinol. 12:421-9.


79. Kam K, Park Y, Cheon M, Son GH, Kim K, Ryu K (2000) Effects of immobilization on estrogen-induced surges of luteinizing hormone and prolactin in ovariectomized rats. Endocrine 12:279-87.


78. Chung JJ, Cho S, KwonYK,KimDH,Kim K (2000) Activation of retinoic acid promotes proliferation of HiB5 hippocampal progenitor cells. Mol Brain Res. 83:52-62.


77. Jeong SJ, Kim HS, Chang KA, Geum DH, Park CH, Seo JH, Rah JC, Lee JH, Choi SH, Lee SG, Kim K, Suh YH (2000) Subcellular localization of presenilins during mouse preimplantation development. FASEB J. 14:2171-6.


76. Lee SG, Heo DS, Yoon SJ, Jee YS, Kang JO, Kim K, Kim CD, Sung MW, Kim NK (2000) Effect of GM-CSF and IL-2 co-expression on the anti-tumor immune response. Anticancer Res. 20:2681-6.


75. Lee SG, Yoon SJ, Kim CD, Kim K, Lim DS, Yeom YI, Sung MW, Heo DS, Kim NK (2000) Enhancement of adenoviral transduction with polycationic liposomes in vivo. Cancer Gene Ther. 7:1329-35.


74. Min JN, Han MY, Lee SS, Kim K, Park YM (2000) Regulation of rat heat shock factor 2 expression during the early organogenic phase of embryogenesis. Bioch Biophy Acta. 1494:256-62.




73. Kang SS, Son GH, Seong JY, Choi D, Kwon HB, Lee CC, Kim K (1998) Noradrenergic neurotoxin suppresses gonadotropin-releasing hormone (GnRH) and its receptor gene expression in ovariectomized, steroid-treated rats. J Neuroendocrinol. 10:911-8.


72. Han YG, Kang SS, Seong JY, Geum D, Kim K (1999) Negative regulation of gonadotropin-releasing hormone and gonadotropin-releasing hormone receptor gene expression by a gonadotrophin- releasing hormone agonist in the rat hypothalamus. J Neuroendocrinol. 11:195-201.


71. Seong JY, Park S, Kim K (1999) Enhanced splicing of the first intron from the gonadotropin-releasing hormone (GnRH) primary transcript is a prerequisite for mature GnRH messenger RNA: presence of GnRH neuron-specific splicing factors. Mol Endocrinol. 13:1882-95.


70. Cheon M, Park D, Kim K, Park SD, Ryu K (1999) Homologous upregulation of GnRH receptor mRNA by continuous GnRH in cultured rat pituitary cells. Endocrine 11:49-55.


69. Kim MO, Koh PO, Kim JH, Kim JS, Kang SS, Cho GJ, Kim K, Choi WS (1999) Localization of dopamine D1 and D2 receptor mRNAs in the rat systemic and pulmonary vasculatures. Mol Cells. 9:417-21.




68. Seong JY, Kang SS, Kam K, Han YG, Kwon HB, Ryu K, Kim K (1998) Differential regulation of gonadotropin-releasing hormone (GnRH) receptor expression in the posterior mediobasal hypothalamus by steroid hormones: Implication of GnRH neuronal activity. Mol Brain Res. 53:226-35.


67. Cho S, Cho H, Geum D, Kim K (1998) Retinoic acid regulates gonadotropin- releasing hormone (GnRH) release and gene expression in the rat hypothalamic fragments and GT1-1 neuronal cells in vitro. Mol Brain Res. 54:74-84.


66. Jung N, Sun W, Lee H, Cho S, Shim C, Kim K (1998) Gonadotropin-releasing hormone (GnRH) gene regulation by N-methyl-D-aspartic acid in GT1-1 neuronal cells: Differential involvement of c-fos and c-jun protooncogens. Mol Brain Res. 61:162-9.


65. Lee CS, Kim K, Yu DY, Lee KK (1998) Pretreatment with glucocorticoid is essential for lactogenic induction of the bovine beta-casein/CAT expression in HC11 cells. Endocr Res. 24:65-77.




64. Cho S, Han J, Sun W, Choi D, Kwon HB, Jarry H, Wuttke W, Kim K (1997) Evidence for autocrine inhibition of GnRH gene transcription by GnRH in hypothalamic GT1-1 neuronal cells. Mol Brain Res. 50:51-8.


63. Sun W, Jarry H, Wuttke W, Kim K (1997) Gonadotropin-releasing hormone (GnRH) modulates gamma aminobutyric acid-evoked intracellular calcium increase in immortalized hypothalamic GnRH neurons. Brain Res. 747:70-7.


62. Jeong SJ, Kim K, Suh YH (1997) Age-related changes in the expression of amyloid precusor protein (APP) in the brain of senescence accereated mouse (SAM) P/10. Neuroreport 8:1733-7.


61. Sun W, Choe YS, Lee YJ, Kim K (1997) Suppression of GnRH gene expression in GT1-1 hypothalamic neuronal cells: action of protein kinase C. Neuroreport 8:3541-6.


60. Kim AJ, Cha GH, Kim K, Gilbert LI, Lee CC (1997) Purification and characterization of the prothoracicotropic hormone of Drosophila melanogaster. Proc Natl Acad Sci USA. 94:1130-5.


59. Kim K, Seong JY, Kang SS, Sun W (1997) 'Neuroendocrine regulation of GnRH gene expression' In: IS Parhar and Y Sakuma ed. "GnRH Neurons: Gene to Behavior", Brain Shuppan Publ Co Tokyo. pp. 401-27. (Review)


58. Geum D, Sun W, Paik SK, Lee CC, Kim K (1997) Estrogen-induced cyclin D1 and D3 gene expression during mouse uterine cell proliferation in vivo: Differential induction mechanism of cyclin D1 and D3. Mol Reprod Dev. 46:450-8.


57. Choe YS, Shim C, Choi D, Lee CS, Lee KK, Kim K (1997) Expression of galectin-1 mRNA in the mouse uterus is under the control of ovarian steroids during blastocyst implantation. Mol Reprod Dev. 48:261-6.


56. Shim C, Choi D, Kwon HB, Kim K (1997) Expression of laminin chain-specific gene transcripts in mouse uterine tissues during peri-implantation period. Mol Reprod Dev. 48:176-84.


55. Shim C, Lee SG, Song WK, Lee CS, Lee KK, Kim K (1997) Laminin chain-specific gene expression during mouse oocyte maturation. Mol Reprod Dev. 48:185-93.


54. Kim J, Yu MH, Kim K (1997) Repression participates in mammary tissue-specific activation of the caprine beta-lactoglobulin promoter. Mol Cell Endocrinol. 133:161-8.


53. Roth C, Jung H, Kim K, Arias P, Moguilevsky J, Jarry H, Leonhardt S, Wuttke W (1997) Involvement of gamma amino butyric acid (GABA) in the postnatal function of the GnRH pulse generator as determined on the basis of GnRH and GnRH-receptor gene expression in the hypothalamus and the pituitary. Exp Clin Endocrinol Diabetes. 105:353-8.


52. Park D, Kim C, Cheon M, Kim K, Ryu K (1997) cAMP and protein kinase C elevate LH mRNA levels by activating transcription rather than stabilizing mRNA in rat pituitary cells. Mol Cells. 7:98-103.


51. Cho BN, Kim K (1997) Differential effect of baclofen on hypothalamic GnRH and pituitary LH gene expression in steroid-treated rats. Mol Cells. 7:605-9.




50. Sun W, Lee DK, Lee CC, Kim K (1996) Differential expression of D-type G1 cyclins during mouse development and liver regeneration in vivo. Mol Reprod Dev. 43: 414-20.


49. Shim C, Kwon HB, Kim K (1996) Differential expression of laminin chain-specific transcripts during mouse preimplantation embryo development. Mol Reprod Dev. 44:44-55.


48. Lee DK, Sun W, Rhee K, Thompson EA, Lee CC, Kim K (1996) Regulation of the thymidine kinase gene expression during liver regeneration and uterine tissue proliferation. Transgenics 2:89-98.


47. Seong JY, Kim K (1996) Measurement of GnRH mRNA levels by Northern blot hybridization assay and competitive RT-PCR in the rat preoptic area. Neuroscience Protocols 3:1-17.


46. Wuttke W, Jarry H, Feleder C, Moguilevsky J, Leonhardt S, Seong JY, Kim K (1996) The neurochemistry of the GnRH pulse generator. Acta Neurobiol Exp. 56:707-13.


45. Park D, Cheon M, Kim C, Kim K, Ryu K (1996) Progesterone together with estradiol promotes luteinizing hormone beta-subunit mRNA stability in rat pituitary cells cultured in vitro. Eur J Endocrinol. 134:236-42.


44. Lee CS, Kim K, Yu DY, Lee KK (1996) An efficient expression of human growth hormone (hGH) in the milk of transgenic mice using rat beta-casein/hGH fusion genes. Appl Biochem Biotechnol. 56:211-22.


43. Chung YD, Kwon HC, Chung KW, Kim SJ, Kim K, Lee CC (1996) Identification of ovarian enhancer-binding factors which bind to ovarian enhancer 1 of the Drosophila genes yp1 and yp2. Mol Gen Genet. 251:347-51.




42. Kang SH, Seong JY, Cho S, Cho H, Kim K (1995) Acute increase in GABAergic neurotransmission exerts a stimulatory effect on GnRH gene expression in ovariectomized estrogen and progesterone treated adult female rats. Neuro- endocrinology 61:486-92.


41. Kim DS, Yoon JH, Ahn SK, Kim KE, Seong RH, Hong SH, Kim K, Ryu K, Park SD (1995) A 33 kDa Pit-1-like protein binds to the distal region of the human thyrotropin alpha-subunit gene. J Mol Endocrinol. 14:313-22.


40. Leonhardt S, Seong JY, Kim K, Thorun Y, Wuttke W, Jarry H (1995) Activation of central GABAA- but not of GABAB-receptor causes a rapid reduction of GnRH gene expression in the preoptic/anterior hypothalamic area of ovariectomized rats. Neuroendocrinology 61:655-62.


39. Seong JY, Jarry H, Kuhnemuth S, Leonhardt S, Wuttke W, Kim K (1995) Effect of GABAergic compounds on GnRH receptor gene expression in the rat. Endocrinology 136:2587-93.


38. Kim J, Kim J-Y, Kim K, Yu M-H (1995) Isolation and characterization of the caprine genomic beta-lactoglobulin gene. Mol Cells 5: 209-216.


37. Chung YD, Kwon HB, Chung KW, Kim SJ, Choe OM, Yong N, Kim K, Lee CC (1995) Regulation of yolk protein 2 gene expression in Drosophila immigrans. Mol Cells 5: 325-329.




36. Kim K, Lee BJ. Cho BN, Kang SS, Choi WS, Park SD, Lee CC, Cho WK, Wuttke W (1994) A blockade of noradrenergic neurotransmission with diethyldithiocarbamic acid decreases mRNA level of gonadotropin releasing- hormone (GnRH) in the hypothalamus of ovariectomized, steroid-treated prepubertal rats. Neuroendo- crinology 59:539-44.


35. Suh J, Song ES, Kim C, Yu MH, Kim K (1994) Cross-talk between N-methyl-D-aspartate and adrenergic neurotransmission in the regulation of hypothalamic GnRH gene expression. Brain Res. 645:36-40.


34. Choi WS, Kim MO, Lee BJ, Kim JH, Sun W, Seong JY, Kim K (1994) Presence of gonadotropin-releasing hormone mRNA in the rat olfactory piriform cortex. Brain Res. 648:148-51.


33. Yoon M, Seong JY, Song E, Ryu K, Kim K (1994) Temporal changes in LHRH and LH subunit messenger RNA level in response to testosterone in castrated adult rats. Neuroendo Lett. 16: 89-95.


32. Yoon M, Lee DK, Ryu K, Lee CC, Kim K (1994) Effect of testosterone and its metabolites on LHRH and LH gene expression in castrated adult rats. Neuroendo Lett. 16:97-102.


31. Lee DK, Sun W, Lim C, Rhee K. Thompson EA, Lee CC, Cho WK, Kim K (1994) Murine thymidine kinase in transgenic mice. Transgenics 1:337-47.


30. Cho BN, Seong JY, Cho H, Kim K (1994) Progesterone stimulates GnRH gene expression in the hypothalamus of ovariectomized, estrogen treated adult rats. Brain Res. 652:177-80.


29. Lee DK, Sun W, Rhee K, Cho H, Lee CC, Kim K (1994) Analysis of thymidine kinase gene expression in preimplantation mouse embryos. Mol Reprod Dev. 39:259-67.


28. Lee SH, Song ES, Yu SK, Kim C, Lee DK, Choi WS, Lee CC, Kim K(1994) Temporal changes in ovarian gonadotropin-releasing hormone mRNA levels by gonadotropins in the rat. Mol Cells 4: 39-44.


27. Choi WS, Lee SH, Yu SK, Baik SH, Lee CC, Kim K(1994) Expression and cellular localization of gonadotropin releasing hormone in the rat gonad. Mol Cells 4: 267-272.


26. Lee SH, Choi WS, Kim C, Kang HM, Geum D, Park H-S, Park YM, Lee CC, Kim K (1994) A local regulation of GnRH release and gene expression in rat granulosa cells by endogenous opioid peptide and GnRH analogues. Mol Cells 4: 473-479.




25. Cho BN, Suh YH, Yoon YD, Lee CC, Kim K (1993) Progesterone inhibits the estrogen-induced prolactin gene expression in the rat pituitary. Mol Cell Endocrinol. 93:47-52.


24. Kim K, Lim IS, Cho BN, Kang SS, Lee BJ, Choi KH, Chung CH, Lee CC, Cho WK, Wuttke W (1993) A partial blackade of catecholaminergic neurotransmission with 6-hydroxydopamine decreases mRNA level of gonadotropin releasing hormone in the male rat hypothalamus. Neuroendocrinology 58:146-52.


23. Seong JY, Lee YK, Lee CC, Kim K (1993) NMDA receptor antagonist decreases the progesterone-induced increase in GnRH gene expression in the rat hypothalamus. Neuroendocrinology 58:234-9.


22. Kwon HB, Ahn RS, Lee WK, Im WB, Lee CC, Kim K (1993) Changes in the activities of steroidogenic enzymes during the development of ovarian follicles in Rana nigromaculata. Gen Com Endocrinol. 92:225-32.


21. Kim K, Jarry H, Knoke I, Seong JY, Leonhardt S, Wuttke W (1993) Competitive PCR for quantitation of GnRH mRNA level in a single micropunch of the rat preoptic area. Mol Cell Endocrinol. 97:153-8.




20. Shim C, Lee DK, Lee CC, Cho WK, Kim K (1992) Inhibitory effect of purines in meiotic maturation of denuded mouse oocytes. Mol Reprod Dev. 31:280-6.


19. Pak JW, Chung KW, Lee CC, Kim K, Namkoog Y, Koolman J (1992) Evidence for multiple forms of the prothoracicotropic hormone in Drosophila melanogaster and identification of a new function. J Insect Physiol. 38:167-76.


18. Choi H, Kim K, Choi K (1992) Effect of nicotine on the regulation of tyrosine hydroxylase gene expression in PC12 cells. Mol Cells 1: 421-424.




17. Kang HM, Cho C, Lee KK, Kwon HB, Kim K, Cho WK (1991) Protein modification by phosphorylation during the process of nuclear membrane dissolution in puromycin-treated mouse oocytes. Biol Reprod. 44:590-8.


16. Seol JH, Woo SK, Jung EM, Yoo SJ, Lee CS, Kim K, Tanaka K, Ichihara A, Ha DB, Chung CH (1991) Protease Do is essential for survival of Escherichia coli at high temperature: Its identity with the htrA gene product. Biochem Biophys Res Commun. 176:730-6.


15. Kim K, Lee BJ, Lee CC, Cho WK, Ramirez VD (1991) Adrenergic mediation of the naloxone-induced GnRH release from hypothalami of ovariectomized, steroid-treated immature rats. Acta Endocrinol. 125:680-6.


14. Park KS, Cho CH, Lee KK, Kim K, Lee CC, Cho WK (1991) Temporal relationship between histone H1 kinase activity and maturation promoting factor activity during mouse oocyte maturation. Mol Cells 1: 197-201.


13. Baik SH, Choi YS, Ahn H, Kim K, Lee CC, Cho WK (1991) Effects of estrogen and dopamine on prolactin synthesis in the rat pituitary: Immunohistochemistry and in situ hybridization. Mol Cells 1: 307-315.




12. Lee BJ, Kim K, Cho WK (1990) Activation of intracellular pathways with forskolin and phorbol ester increases LHRH mRNA level in the rat hypothalamus superfused in vitro. Mol Brain Res. 8:185-91.


11. Kang HM, Kim K, Kwon HB, Cho WK (1990) Regulation of laminin gene expression in the expansion of mouse blastocyst. Mol Reprod Dev. 27:191-9.




10. Kim J, Kim HK, Kim K, Kim SR, Cho WK (1989) Multiple forms of alkaline phosphatase in mouse preimplantation embryos. J Reprod Fertil. 86:65-72.


9. Kim K, Lee BJ, Park Y, Cho WK (1989) Progesterone increases messenger ribonucleic acid (mRNA) encoding luteinizing hormone releasing hormone (LHRH) level in the hypothalamus of ovariectomized estradiol-primed prepubertal rats. Mol Brain Res. 6:151-8.




8. Park Y, ParkSD,ChoWK,Kim K (1988) Testosterone stimulates LH-RH-like mRNA level in the rat hypothalamus. Brain Res. 451:255-60.


7. Kim K, Lee CS, Cho WK, Ramirez VD (1988) Effect of chronic administration of progesterone on the naloxone-induced LHRH release from hypothalami of ovariectomized, estradiol-primed prepubertal rats. Life Sci. 43:609-13.




6. Kim K, Ramirez VD (1986) Effects of prostaglandin E2, forskolin and cholera toxin on cyclic AMP production and in vitro LHRH release from the rat hypothalamus. Brain Res. 386:258-65.


5. Kim K, Ramirez VD (1986) In vitro LHRH release from superfused hypothalamus as a function of the rat estrous cycle: effect of progesterone. Neuroendocrinology 42:392-8.




4. Kim K, Ramirez VD (1985) In vitro luteinizing hormone releasing hormone (LHRH) release from superfused rat hypothalami: Site of action of progesterone and effect of estrogen. Endocrinology 116:252-8.


3. Kim K, Ramirez VD (1985) Dibutyryl cyclic adenosine monophosphate stimulates in vitro luteinizing hormone-releasing hormone release only from median eminence derived from ovariectomized, estradiol-primed rats. Brain Res. 342:154-7.


2. Ramirez VD, Kim K, Dluzen D (1985) Progesterone action on the LHRH and the nigrostriatal dopamine neuronal systems: In vitro and in vivo studies. Recent Prog Horm Res. 41:421-72.




1. Kim K, Ramirez VD (1982) In vitro progesterone stimulates the release of luteinizing hormone-releasing hormone from superfused hypothalamic tissue from ovariectomized estradiol-primed prepuberal rats. Endocrinology 111:750-7.