Publication > SCI 논문 list


182. Jeong B, Hong JH, Kim H, Choe HK, Kim K, Lee KJ. (2016). Multi-stability of circadian phase wave within early postnatal suprachiasmatic nucleus. Sci Rep. 6:21463.

181. Row H, Jeong J, Cho S, Kim S, Kim K. (2016). HL271, a novel chemical compound derived from metformin, differs from metformin in its effects on the circadian clock and metabolism. Biochem Biophys Res Commun. 469(3):783-9.

180. Lee J, Lee S, Chung S, Park N, Son GH, An H, Jang J, Chang DJ, Suh YG, Kim K.  (2016). Identification of a novel circadian clock modulator controlling BMAL1 expression through a ROR/REV-ERB-response element-dependent mechanism. Biochem Biophys Res Commun. 469(3):580-6.



179. Chun SK, Chung S, Kim HD, Lee JH, Jang J, Kim J, Kim D, Son GH, Oh YJ, Suh YG, Lee CS, Kim K. (2015). A synthetic cryptochrome inhibitor induces anti-proliferative effects and increases chemosensitivity in human breast cancer cells. Biochem Biophys Res Commun. 467(2):441-6.

178. Lee Y, Chun SK, Kim K. (2015). Sumoylation controls CLOCK-BMAL1-mediated clock resetting via CBP recruitment in nuclear transcriptional foci. Biochim Biophys Acta. 1853(10 Pt A):2697-708.

177. Park N, Kim HD, Cheon S, Row H, Lee J, Han DH, Cho S, Kim K. (2015). A Novel Bmal1 Mutant Mouse Reveals Essential Roles of the C-Terminal Domain on Circadian Rhythms. PLos One. 10(9):e0138661.

176. Koo J, Cheo HK, Kim HD, Chun SK, Son GH, Kim K. (2015). Effect of Mefloquine, a Gap Junction Blocker, on Circadian Period2 Gene Oscillation in the Mouse Suprachiasmatic Nucleus Ex Vivo. Endocrinol Metab (Seoul). 30(3):361-70.

175. Lee J, Chun SK, Son GH, Kim K. (2015). Sumoylation of Hes6 Regulates Protein Degradation and Hes1-Mediated Transcription. Endocrinol Metab (Seoul). 30(3):381-8.

174. Song H, Moon M, Choe HK, Han DH, Jang C, Kim A, Cho S, Kim K, Mook-Jung I. (2015). Aβ-induced degradation of BMAL1 and CBP leads to circadian rhythm disruption in Alzheimer's disease. Mol Neurodegener. 10:13.

173. Choe, HK, Chun SK, Kim J, Kim D, Kim HD, Kim K. (2015). Real-Time GnRH Gene Transcription in GnRH Promoter-Driven Luciferase-Expressing Transgenic Mice: Effect of Kisspeptin. Neuroendocrinology. 102(3):194-9.



172. Chung S, Lee EJ, Yun S, Choe HK, Park SB, Son HJ, Kim KS, Dluzen DE, Lee I, Hwang O, Son GH, Kim K. (2014). Impact of Circadian Nuclear Receptor REV-ERBa on Midbrain Dopamine Production and Mood Regulation. Cell. 157(4)858-68.

171. Nam HJ, Boo K, Kim D, Han DH, Choe HK, Kim CR, Sun W, Kim H, Kim K, Lee H, Metzger E, Schuele R, Yoo SH, Takahashi JS, Cho S, Son GH, Baek SH. (2014). Phosphorylation of LSD1 by PKCα Is Crucial for Circadian Rhythmicity and Phase Resetting. Mol Cell. 53(5):791-805.

170. Han DH, Lee YJ, Kim K, Kim CJ, Cho S. (2014). Modulation of glucocorticoid receptor induction properties by core circadian clock proteins. Mol Cell Endocrinol. 383(1-2):170-80.

169. Chun SK, Jang J, Chung S, Yun H, Kim NJ, Jung JW, Son GH, Suh YG, Kim K. (2014). Identification and Validation of cryptochrome Inhibitors That Modulate the Molecular Circadian Clock. ACS Chem Biol. 9(3):703-10.



168. Cheon S, Park N, Cho S, Kim K. (2013). Glucocorticoid-mediated Period2 induction delays the phase of circadian rhythm. Nucleic Acids Res. 41(12):6161-6174.

167. Choe HK, Kim HD, Park SH, Lee HW, Park JY, Seong JY, Lightman SL, Son GH, Kim K. (2013). Synchronous activation of gonadotropin-releasing hormone gene transcription and secretion by pulsatile kisspeptin stimulation. Proc Natl Acad Sci U S A. 110(14):5677-82.

166. Hwang JI, Moon MJ, Park S, Kim DK, Cho EB, Ha N, Son GH, Kim K, Vaudry H, Seong JY. (2013). Expansion of Secretin-Like G Protein-Coupled Receptors and Their Peptide Ligands via Local Duplications before and After Two Rounds of Whole-Genome Duplication. Mol Biol Evol. 30(5):1119-30.



165. Choi EW, Seen DS, Song YB, Son HS, Jung NC, Huh WK, Hahn JS, Kim K, Jeong JY, Lee TG. (2012). AdHTS: a high-throughput system for generating recombinant adenoviruses. J Biotechnol. 162(2-3):246-52.

164. Yoon JA, Han DH, Noh JY, Kim MH, Son GH, Kim K, Kim CJ, Pak YK, Cho S. (2012). Meal time shift disturbs circadian rhythmicity along with metabolic and behavioral alterations in mice. PLoS One. 7(8):e44053.

163. Kim H, Park JH, Kim K. (2012). Lipid-like components released from degenerating dopaminergic neurons trigger the dynamic migration of microglia. Biochem Biophys Res Commun. 426(1):18-25.

162. Park N, Cheon S, Son GH, Cho S, Kim K. (2012). Chronic circadian disturbance by a shortened light-dark cycle increases mortality. Neurobiol Aging. 33(6):1122.e11-22.



161. Moon MJ, Kim HY, Park S, Kim DK, Cho EB, Park CR, You DJ, Hwang JI, Kim K, Choe H, Seong JY. (2011). Evolutionary conserved residues at the GLP-1 receptor core confer ligand-induced receptor activation. J Biol Chem. 287(6):3873-84.

160. Kim TW, Moon Y, Kim K, Lee JE, Koh HC, Rhyu IJ, Kim H, Sun W. (2011). Dissociation of progressive dopaminergic neuronal death and behavioral impairments by bax deletion in a mouse model of Parkinson's diseases. PLoS One. 6(10):e25346.

159. Son GH, Chung S, Kim K. (2011). The adrenal peripheral clock: glucocorticoid and the circadian timing system. Front Neuroendocrinol. 32(4):451-65.

158. Park E, Iaccarino C, Lee J, Kwon I, Baik SM, Kim M, Seong JY, Son GH, Borrelli E, Kim K. (2011). Regulatory roles of heterogeneous nuclear ribonucleoprotein M and Nova-1 in the alternative splicing of the dopamine D2 receptor pre-mRNA. J Biol Chem. 286(28):25301-8.

157. Lee EJ, Son GH, Chung S, Lee S, Kim J, Choi S, Kim K. (2011). Impairment of fear memory consolidation in maternally stressed male mouse offspring: evidence for nongenomic glucocorticoid action on the amygdala. J Neurosci. 31(19):7131-40.

156. Kim HD, Choe HK, Chung S, Kim M, Seong JY, Son GH, Kim K. (2011). Class-C SOX Transcription Factors Control GnRH Gene Expression via the Intronic Transcriptional Enhancer. Mol Endocrinol. 25(7):1184-96.

155. Moon Y, Kim JY, Choi SY, Kim K, Kim H, Sun W. (2011). Induction of ezrin-radixin-moesin molecules after cryogenic traumatic brain injury of the mouse cortex. Neuroreport. 22(6):304-8.

154. Eun B, Kim HJ, Kim SY, Kim TW, Hong ST, Choi KM, Shim JK, Moon Y, Son GH, Kim K, Kim H, Sun W. (2011). Induction of Per1 expression following an experimentally induced epilepsy in the mouse hippocampus. Neurosci Lett. 498(2):110-3.

153. Chung S, Son GH, Kim K. (2011). Adrenal peripheral oscillator in generating the circadian glucocorticoid rhythm. Ann N Y Acad Sci. 1220:71-81.

152. Chung S, Son GH, Kim K. (2011). Circadian rhythm of adrenal glucocorticoid: its regulation and clinical implications. Biochim Biophys Acta. 1812(5):581-91.

151. Choe HK, Son GH, Chung S, Kim M, Sun W, Kim H, Geum D, Kim K. (2011). Maternal stress retards fetal development in mice with transcriptome-wide impact on gene expression profiles of the limb. Stress. 14(2):194-204.

150. Kim CH, Leung A, Huh YH, Yang E, Kim DJ, Leblanc P, Ryu H, Kim K, Kim DW, Garland EM, Raj SR, Biaggioni I, Robertson D, Kim KS. (2011). Norepinephrine Deficiency Is Caused by Combined Abnormal mRNA Processing and Defective Protein Trafficking of Dopamine beta-Hydroxylase. J Biol Chem. 286(11):9196-204.

149. Kwon I, Choe HK, Son GH, Kim K. (2011). Mammalian Molecular Clocks. Exp Neurobiol. 20(1):18-28.



148. Moon Y, Choi SY, Kim K, Kim H, Sun W. (2010). Expression of connexin29 and 32 in the penumbra region after traumatic brain injury of mice. Neuroreport. 21(18):1135-9.

147. Lee Y, Lee J, Kwon I, Nakajima Y, Ohmiya Y, Son GH, Lee KH, and Kim K. (2010). Coactivation of the CLOCK-BMAL1 complex by CBP mediates resetting of the circadian clock. J Cell Sci. 123(Pt 20):3547-57.

146. Eun B, Cho B, Moon Y, Kim SY, Kim K, Kim H, Sun W. (2010). Induction of neuronal apoptosis by expression of Hes6 via p53-dependent pathway. Brain Res. 1313:1-8.



145. Oda A, Katayose Y, Yabuuchi S, Yamamoto K, Mizuma M, Shirasou S, Onogawa T, Ohtsuka H, Yoshida H, Hayashi H, Rikiyama T, Kim H, Choe Y, Kim K, Son H, Motoi F, Egawa S, Unno M. (2009). Clock gene mouse period2 overexpression inhibits growth of human pancreatic cancer cells and has synergistic effect with cisplatin. Anticancer Res. 29(4):1201-9.

144. Park E, Lee MS, Baik SM, Cho EB, Son GH, Seong JY, Lee KH, Kim K. (2009). Nova-1 mediates glucocorticoid-induced inhibition of pre-mRNA splicing of gonadotropin-releasing hormone transcripts. J Biol Chem. 284(19):12792-800.

143. Kim DK, Yang JS, Maiti K, Hwang JI, Kim K, Seen D, Ahn Y, Lee C, Kang BC, Kwon HB, Cheon J, Seong JY. (2009). A gonadotropin-releasing hormone-II antagonist induces autophagy of prostate cancer cells. Cancer Res. 69(3):923-31.

142. Lee YR, Tsunekawa K, Moon MJ, Um HN, Hwang JI, Osugi T, Otaki N, Sunakawa Y, Kim K, Vaudry H, Kwon HB, Seong JY, Tsutsui K. (2009). Molecular evolution of multiple forms of kisspeptins and GPR54 receptors in vertebrates. Endocrinology. 150(6):2837-46.



141. Son GH, Chung S, Choe HK, Kim HD, Baik SM, Lee H, Lee HW, Choi S, Sun W, Kim H, Cho S, Lee KH, Kim K. (2008). Adrenal peripheral clock controls the autonomous circadian rhythm of glucocorticoid by causing rhythmic steroid production. Proc Natl Acad Sci U S A. 105(52):20970-5.

140. Choi YY, Shamosh NA, Cho SH, DeYoung CG, Lee MJ, Lee JM, Kim SI, Cho ZH, Kim K, Gray JR, Lee KH. (2008). Multiple bases of human intelligence revealed by cortical thickness and neural activation. J Neurosci. 28(41):10323-9.

139. Lee J, Lee Y, Lee MJ, Park E, Kang SH, Chung CH, Lee KH, Kim K. (2008). Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex. Mol Cell Biol. 28(19):6056-65.

138. Oh DY, Yoon JM, Moon MJ, Hwang JI, Choe H, Lee JY, Kim JI, Kim S, Rhim H, O'Dell DK, Walker JM, Na HS, Lee MG, Kwon HB, Kim K, Seong JY. (2008). Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92. J Biol Chem. 283(30):21054-64.

137. Eun B, Lee Y, Hong S, Kim J, Lee HW, Kim K, Sun W, Kim H. (2008). Hes6 controls cell proliferation via interaction with CREB binding protein in the PML nuclear body. J Biol Chem. 283(9):5939-49.



136. Kim J, Lee S, Park K, Hong I, Song B, Son G, Park H, Kim WR, Park E, Choe HK, Kim H, Lee C, Sun W, Kim K, Shin KS, Choi S. (2007). Amygdala depotentiation and fear extinction. Proc Natl Acad Sci U S A. 104(52):20955-60.

135. Kim WR, Kim Y, Eun B, Park OH, Kim H, Kim K, Park CH, Vinsant S, Oppenheim RW, Sun W. (2007). Impaired migration in the rostral migratory stream but spared olfactory function after the elimination of programmed cell death in Bax knock-out mice. J Neurosci. 27(52):14392-403.

134. Shim HS, Kim H, Lee J, Son GH, Cho S, Oh TH, Kang SH, Seen DS, Lee KH, Kim K. (2007). Rapid activation of CLOCK by Ca2+-dependent protein kinase C mediates resetting of the mammalian circadian clock. EMBO Rep. 8(4):366-71.

133. Son GH, Chung S, Geum D, Kang SS, Choi WS, Kim K, Choi S. (2007). Hyperactivity and alteration of the midbrain dopaminergic system in maternally stressed male mice offspring. Biochem Biophys Res Commun. 352(3):823-9.



132. Oh DY, Kim K, Kwon HB, Seong JY. (2006). Cellular and molecular biology of orphan G protein-coupled receptors. Int Rev Cytol. 252:163-218.

131. Choi SY, Kim DK, Eun B, Kim K, Sun W, Kim H. (2006). Anti-apoptotic function of thymosin-beta in developing chick spinal motoneurons. Biochem Biophys Res Commun. 346(3):872-8.

130. Jung SR, Kim K, Hille B, Nguyen TD, Koh DS. (2006). Pattern of Ca2+ increase determines the type of secretory mechanism activated in dog pancreatic duct epithelial cells. J Physiol. 576(Pt 1):163-78.

129. Kwon I, Lee J, Chang SH, Jung NC, Lee BJ, Son GH, Kim K, Lee KH. (2006). BMAL1 shuttling controls transactivation and degradation of the CLOCK/BMAL1 heterodimer. Mol Cell Biol. 26(19):7318-30.

128. Kim HS, Yumkham S, Choi JH, Son GH, Kim K, Ryu SH, Suh PG. (2006). Serotonin stimulates GnRH secretion through the c-Src-PLC gamma1 pathway in GT1-7 hypothalamic cells. J Endocrinol. 190(3):581-91.

127. Park JH, Cho H, Kim H, Kim K. (2006). Repeated brief epileptic seizures by pentylenetetrazole cause neurodegeneration and promote neurogenesis in discrete brain regions of freely moving adult rats. Neuroscience. 140(2):673-84.

126. Son GH, Geum D, Chung S, Kim EJ, Jo JH, Kim CM, Lee KH, Kim H, Choi S, Kim HT, Lee CJ, Kim K. (2006). Maternal stress produces learning deficits associated with impairment of NMDA receptor-mediated synaptic plasticity. J Neurosci. 26(12):3309-18.

125. Park E, Han J, Son GH, Lee MS, Chung S, Park SH, Park K, Lee KH, Choi S, Seong JY, Kim K. (2006). Cooperative actions of Tra2alpha with 9G8 and SRp30c in the RNA splicing of the gonadotropin-releasing hormone (GnRH) gene transcript. J. Biol. Chem. 281(1):401-9.

124. Lee KH, Choi YY, Gray JR, Cho SH, Chae JH, Lee S, Kim K. (2006). Neural correlates of superior intelligence: Stronger recruitment of posterior parietal cortex. Neuroimage. 29(2):578-86.



123. Son GH, Geum D, Chung S, Park E, Lee KH, Choi S, Kim K. (2005). A protective role of 27-kDa heat shock protein in glucocorticoid-evoked apoptotic cell death of hippocampal progenitor cells. Biochem Biophys Res Commun. 338(4):1751-8.

122. Lee JS, Zhang MH, Yun EK, Geum D, Kim K, Kim TH, Lim YS, Seo JS. (2005). Heat shock protein 27 interacts with vimentin and prevents insolubilization of vimentin subunits induced by cadmium. Exp Mol Med. 37(5):427-35.

121. Maiti K, Oh DY, Moon JS, Acharjee S, Li JH, Bai DG, Park HS, Lee K, Lee YC, Jung NC, Kim K , Vaudry H, Kwon HB, Seong JY. (2005). Differential Effects of Gonadotropin-Releasing Hormone-I (GnRH-I) and GnRH-II on Prostate Cancer Cell Signaling and Death. J Clin Endocrinol Metab. 90(7):4287-98.

120. Li JH, Sicard F, Salam MA, Baek M, LePrince J, Vaudry H, Kim K, Kwon HB, Seong JY. (2005). Molecular cloning and functional characterization of a type-I neurotensin receptor (NTR) and a novel NTR from the bullfrog brain. J Mol Endocrinol. 34:793-807.

119. Chung S, Son GH, Park SH, Park E, Lee KH, Geum D, Kim K. (2005). Differential adaptive responses to chronic stress of maternally stressed adult mice. Endocrinology. 146: 3202-3210.

118. Khang I, Sonn S, Park JH, Rhee K, Park D, Kim K. (2005). Expression of epithin in mouse preimplantation development: the functional role in compaction. Dev Biol. 281:134-44.

117. Moon Y, Park JH, Lee KH, Kim K. (2005). Mitochondrial membrane depolarization and the selective death of dopaminergic neurons by rotenone: Protective effect of coenzyme Q10. J Neurochem 93(5):1199-208.

116. Li JH, Choe H, Wang AF, Maiti K, Wang C, Salam MA, Chun SY, Lee WK, Kim K, Kwon HB, and Seong JY. (2005). Extracelllar loop 3 (EL3) and EL3-proximal transmembrane helix 7 of the mammalian type I and type II GnRH receptors determine differential ligand selectivity to GnRH-I and GnRH-II. Mol Pharmacol. 67(4):1099-1110.

115. Oh DY, Song JA, Moon JS, Kim JI, Kim K, Kwon HB, Seong JY. (2005). Membrane-proximal region of the carboxyl terminus of the gonadotropin- releasing hormone receptor (GnRHR) confers differential signal transduction between mammalian and nonmammalian GnRHR. Mol Endocrinol. 19(3):722-731.

114. Park CE, Cha KY, Kim K, Lee KA. (2005). Expression of cell cycle regulatory genes during primordial-primary follicle transition in the mouse ovary. Fertil Steril. 83(2):410-8.

113. Son GH, Park E, Jung H, Han J, Lee KH, Seong JY, Kim K. (2005). GnRH pre-mRNA splicing: Solving the mystery of a nature’s knockout, hpg mouse. Biochem Biophys Res Commun. 326(2): 261-7.



111. Achrjee S, Do-Rego J-C, Oh D.Y, Ahn R.S, Choe H, Vaudry H, Kim K, Seong J.Y. and Kwon H.B. (2004). Identification of amino acid residues that direct differential ligand selectivity of mammalian and nonmammalian V1a type receptors for arginine vasopressin and vasotocin: Insights into molecular coevolution of V1a receptors and their ligands. J. Biol. Chem. 279(52):54445-53.

110. Park C.E, Shin M.R, Jeon E.H, Cha K.Y, Lee S.H, Kim K, Kim N.H, and Lee K.A. (2004). Oocyte-selective expression of MTi7 and finding Its role in oocyte maturation and cell division in zygote by RNA interference. Mol. Reprod. Dev. 69(4):365-374.

109. Sonn S, Khang I, Kim K, and Rhee K. (2004). Suppression of Nek2A in mouse early embryos confirms its requirement of chromosome segregation. J. Cell Sci. 117:5557-66.

108. Lee J, Hong J, Kim E, Yoo J.C, Kim K, Ki. S.W, Krishnamurthy H, Chung S.S.W, Wolgemuth D, and Rhee K. (2004). Developmental stage-specific expression of Rbm suggests its involvement in early phase of spermatogenesis. Mol. Human Reprod. 10(4):259-264.

107. Yoo J.C, Chang J.R, Kim S.H, Jang S.K, Wolgemuth D, Kim K, and Rhee K. (2004). NIPI/XB51/NECAB3 is a potential substrate of Nek2, suggesting specific roles of Nek2 in Golgi. Exp. Cell Res. 292(2):393-402.

106. Lee K.H, Park J-Y, and Kim K. (2004). NMDA receptor-mediated calcium influx plays an essential role in myoblast fusion. FEBS Lett. 578:47-52.



105. Choe Y, Son GH, Lee S, Park E, Moon Y, Kim K. (2003). Cell differentiation of GnRH neurons and alternative RNA splicing of GnRH gene transcript. Neuroendocrinology. 77:282-90.

104. Son GH, Jung H, Seong JY, Choe Y, Geum D, Kim K. (2003). Excision of the first intron from the gonadotropin-releasing hormone (GnRH) transcript serves as a key regulatory step for GnRH biosynthesis. J Biol Chem. 278:18037-44.

103. Choe Y, Jung H, Kim K. (2003). Selective roles of protein kinase C isoforms on cell migration of immortalized hypothalamic neurons. J Neuroendocrinol. 15(5):508-515.

102. Lee S, Lee SA, Shim C, Khang I, Lee KA, Park YM, Kang BM, Kim K. (2003). Identification of estrogen-regulated genes in the mouse uterus using a delayed implantation model. Mol. Reprod. Develop. 64:405-413.

101. Jung H, Choe Y, Kim H, Park N, Son GH, Khang I, Kim K. (2003). Involvement of clock:bmal1 heterodimer in serum responsive mPer1 induction. Neuroreport. 14:15-19.

100. Seong JY, Wang L, Oh DY, Yun O, Maiti K, Li J, Soh JM, Choi HS, Kim K, Vaudry H, Kwon HB. (2003). Ala/Thr201 in extracellular loop 2 and leu/phe(290) in transmembrane domain 6 of type-1 frog gonadotropin-releasing hormone (GnRH) receptor confer differential ligand sensitivity and signal transduction. Endocrinology. 144:454-66.



99. Choe Y, Lee BJ, Khang I, Kim K. (2002). Participation of protein kinase C alpha isoform and extracellular signal-regulated kinase in neurite outgrowth of GT1 hypothalamic neurons. J. Neurochem. 83:1412-22.

98. Kim H, Ha CM, Choi J, Choi EJ, Jeon J, Kim C, Park SK, Kang SS, Kim K, Lee BJ. (2002). Ontogeny and the possible function of a novel epidermal growth factor-like repeat domain-containing protein, NELL2, in the rat brain. J. Neurochem. 83:1389-1400.

97. Kim G. Choe Y, Park J, Cho S, Kim K. (2002). Activation of protein kinase a pathway induces neuronal differentiation of HiB5 hippocampal progenitor cells. Mol. Brain. Research. 109:134-145.

96. Dluzen D, Park JH, Kim K. (2002). Modulation of olfactory bulb tyrosine hydroxylase and catecholamine transporter mRNA by estrogen. Mol. Brain. Research. 108:121-8.

95. Seong JY, Han J, Park S, Wuttke W, Jarry H, Kim K. (2002). Exonic splicing enhancer-dependent splicing of the gonadotropin-releasing hormone premessenger ribonucleic acid is mediated by tra2alpha, a 40 kilodalton serine-arginine-rich (SR) protein. Mol. Endocrinology. 16:2426-38.

94. Han J, Son GH, Seong JY, Kim K. (2002). GnRH pre-mRNA splicing: Role of exonic splicing enhancer. Prog. Brain. Res. 141:209-19.

93. Kim MS, Hur MK, Son YJ, Park JI, Chun SY, D'Elia AV, Damante G, Cho S, Kim K, Lee BJ. (2002), Regulation of pituitary adenylate cyclase- activating polypeptide gene transcription by TTF-1, a homeodomain-containing transcription factor. J. Biol. Chem. 277:36863-71.

92. Geum D, Son GH, Kim K. (2002). Phosphorylation-dependent cellular localization and thermoprotective role of hsp25 in hippocampal HiB5 cells. J. Biol. Chem. 277:19913-21.

91. Park JY, Lee D, Maeng JU, Koh DS, Kim K. (2002). Hyperpolarization, but not depolarization increases intracellular Ca 2+ levels in cultured chick myoblast. Biochem. Biophys. Res. Commun. 290:1176-82.

90. Kim CD, Choe Y, Shim C, Kim K. (2002). Interferone beta secreted from human hair dermal papillar cells inhibits the growth of outer root sheath cells cultured in vitro. Biochem. Biophys. Res. Commun. 290:1133-8.

89. Kim M, Geum D, Khang I, Park YM, Kang BM, Lee KA, Kim K. (2002). Expression pattern of hsp25 in mouse preimplantation embryo: Heat shock responses during oocyte maturation. Mol. Reprod. Develop. 61:3-13.



88. Choi EJ, Ha CM, Choi J, Kang SS, Choi WS, Park SK, Kim K, Lee BJ. (2001). Low-density cDNA array-coupled to PCR differential display identifies new estrogen-responsive genes during the postnatal differentiation of the rat hypothalamus. Mol. Brain. Research. 97: 115-28.

87. Son GH, Geum H, Jung H, Kim K. (2001). Glucocorticooid inhibits growth factor-induced differentiation of hippocampal progenitor HiB5 cells. J. Neurochem. 79:1013-21.

86. Seong JY, Kim BW, Park S, Kim K. (2001). First intron excision of GnRH Pre-mRNA during postnatal development of normal mice and adult hypogonadal mice. Endocrinology. 142:4454-61.

85. Park S, Seong JY, Son GH, Kang SS, Lee S, Kim SR, Kim K. (2001). Analysis of steroid-induced genes in the rat preoptic area-anterior hypothalamus using a differential-display reverse transcriptase-polumerase chain reaction. J. Neuroendocrinol. 13:531-9.

84. Sun W, Lee H, Choe Y, Cho S, Kim DH, Kim K. (2001). Evidence for direct involvement of beta-catenin in phorbol ester-induced neurite outgrowth in GT1-1 hypothalamic neurons. J. Neuroendocrinol. 13:249-60.

83. Cho S, Chung J, Rhee K, Lee BJ, Kim DH, Rhee K, Kim K. (2001). 9-cis-Retinoic acid represses gonadotropin-releasing hormone (GnRH) gene transcription via proximal promoter elements that are distinct from all-trans-retinoic acid response element. Mol. Brain. Research. 87:214-22.

82. Cho S, Chung J, Choi HS, Rhee K, Kim DH, Rhee K, Kim K. (2001). A functional retinoic acid response element (RARE) is present within the distal promoter sequence of the rat gonadotropin-releasing hormone (GnRH) gene. Mol. Brain. Research. 87:204-13.

81. Han J, Seong JY, Kim K, Wuttke W, Jarry H. (2001). Analysis of exonic splicing enhancers in the mouse gonadotropin-releasing hormone (GnRH) gene. Mol. Cell. Endocrinol. 173:157-66.



80. Min JN, Han MY, Lee SS, Kim K, Park YM. (2000). Regulation of rat heat shock factor 2 expression during the early organogenic phase of embryogenesis. Biochim. Biophys. Acta. 1494(3):256-62.

79. Lee SG, Yoon SJ, Kim CD, Kim K, Lim DS, Yeom YI, Sung MW, Hae D, Kim NK. (2000). Enhancement of adenoviral transduction with polycationic liposomes in vivo. Gene Therapy. 7(10):1329-35.

78. Lee SG, Han DS, Yoon SJ, Jee YS, Kang JO, Kim K, Kim CD, Sung MW, Kim NK. (2000). Effect of GM-CSF and IL-2 co-expression on the anti-tumor immune response. Anticancer Res. 20(4):2681-6.

77. Jeong SJ, Kim HS, Chang KA, Geum D, Park CH, Seo JH, Rah JC, Lee JH, Choi SH, Lee SG, Kim K, Suh YH. (2000). Subcellular localization of presenilins during mouse preimplantation development. FASEB J. 14(14):2171-2176.

76. Chung J, Cho S, Kwon YK, Kim DH, Kim K. (2000). Activation of retinoic acid promotes proliferation of HiB5 hippocampal progenitor cells. Mol. Brain Research. 83(1-2):52-62.

75. Kam K, Park Y, Cheon M, Son KH, Kim K, Ryu K. (2000). Effects of immobilization on estrogen-induced surges of luteinizing hormone and prolactin in ovariectomized rats. Endocrine. 12(3):279-287.

74. Kang SS, Kim SR, Leonhard S, Jarry H, Wuttke W, Kim K. (2000). Effect of interleukin-1 on gonadotropin-releasing hormone (GnRH) and GnRH receptor gene expression in castrated male rats. J. Neuroendocrinol. 12(5):421-429.



73. Kim MO, Koh PO, Kim JH, Kim JS, Kang SS, Cho GJ, Kim K, Choi WS. (1999). Localization of dopamine D1 and D2 receptor mRNAs in the rat systemic and pulmonary vasculatures. Mol. Cells. 9(4):417-421.

72. Cheon M, Park D, Kim K, Park SD, Ryu K. (1999). Homologous upregulation of GnRH receptor mRNA by continuous GnRH in cultured rat pituitary cells. Endocrine. 11(1):49-55.

71. Seong JY, Park S, Kim K. (1999). Enhanced splicing of intron A from the gonadotropin-releasing hormone (GnRH) primary transcript is prerequisite form mature GnRH mRNA: Presence of a GnRH neuron-specific splicing factor. Mol. Endocrinol. 13(11):1882-1895.

70. Han YG, Kang SS, Seong JY, Geum D, Kim K. (1999). Negative regulation of gonadotropin-releasing hormone (GnRH) and GnRH receptor gene expression by a GnRH agonist in the hypothalamus. J. Neuroendocrinol. 11(3):195-201.



69. Kang SS, Seong JY, Choi D, Kwon HB, Lee CC, Kim K. (1998). Noradrenergic neurotoxin suppresses gonadotropin-releasing hormone (GnRH) and its receptor gene expression in ovariectomized, steroid-treated rats. J. Neuroendocrinol. 10(12):911-918.

68. Lee CS, Kim K, Yu DY, Lee KK. (1998). Pretreatment with glucocorticoid is essential for lactogenic induction of the bovine beta-casein/CAT expression in HC11 cells. Endocrine Res. 24(1):65-77.

67. Jung N, Sun W, Lee H, Cho S, Shim C, and Kim K. (1998). Gonadotropin-releasing hormone (GnRH) gene regulation by N-methyl-D-aspartic acid in GT1-1 neuronal cells: Differential involvement of c-fos and c-jun protooncogens. Mol. Brain Research. 61(1-2):162-169.

66. Cho S, Cho H, Kwon HB, Kim K. (1998). Retinoic acid regulates gonadotropin-releasing hormone (GnRH) release and gene expression in the rat hypothalamic fragments and GT1-1 neuronal cells in vitro. Mol. Brain Research. 54(1):74-84.

65. Seong JY, Kang SS, Kam K, Han YG, Kwon HB, Ryu K, Kim K. (1998). Differential regulation of gonadotropin-releasing hormone (GnRH) receptor expression in the posterior mediobasal hypothalamus by steroid hormones: Implication of GnRH neuronal activity. Mol. Brain Research. 53(1-2):226-235.



64. Cho BN, Kim K. (1997). Differential effect of baclofen on hypothalamic GnRH and pituitary LH gene expression in steroid-treated rats. Mol. Cells. 7(5):605-609.

63. Park D, Kim C, Cheon M, Kim K, Ryu K. (1997). cAMP and protein kinase C elevate LH mRNA levels by activating transcription rather than stabilizing mRNA in rat pituitary cells. Mol. Cells. 7(1):98-103.

62. Roth C, Jung H, Kim K, Arias P, Moguilevsky J, Jarry H, Leonhardt S, Wuttke W. (1997). Involvement of gamma amino butyric acid (GABA) in the postnatal function of the GnRH pulse generator as determined on the basis of GnRH and GnRH-receptor gene expression in the hypothalamus and the pituitary. Exp. Clin. Endocrinol. Diabetes. 105(6):353-358.

61. Kim J, Yu MH, Kim K. (1997). Repression participates in mammary tissue-specific activation of the caprine gammer-lactoglobulin promoter. Mol. Cell Endocrinol. 133(2):161-168.

60. Shim C, Lee SG, Song WK, Lee CS, Lee KK, Kim K. (1997). Laminin chain-specific gene expression during mouse oocyte maturation. Mol. Reprod. Develop. 48(2):185-193.

59. Shim C, Choi D, Kwon HB, Kim K. (1997). Expression of laminin chain-specific gene transcripts in mouse uterine tissues during peri-implantation period. Mol. Reprod. Develop. 48(2):176-184.

58. Choe YS, Shim C, Choi D, Lee CS, Lee KK, Kim K. (1997). Expression of galectin-1 mRNA in the mouse uterus is under the control of ovarian steroids during blastocyst implantation. Mol. Reprod. Develop. 48(2):261-266.

57. Geum D, Sun W, Paik SK, Lee CC, Kim K. (1997). Estrogen-induced cyclin D1 and D3 gene expression during mouse uterine cell proliferation in vivo: Differential induction mechanism of cyclin D1 and D3. Mo.l Reprod. Develop. 46(4):450-458.

56. Kim K, Seong JY, Kang SS, Sun W. (1997). 'Neuroendocrine regulation of GnRH gene expression' In: I.S. Parhar and Y. Sakuma ed. "GnRH Neurons: Gene to Behavior", Brain Shuppan Publ. Co., Tokyo. pp.401-427. (Review)

55. Kim AJ, Cha GH, Kim K, Gilbert LI, Lee CC. (1997). Purification and characterization of the prothoracicotropic hormone of Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 94(4):1130-5.

54 Sun W, Choe YS, Lee YJ, Kim K. (1997). Repression of GnRH gene expression in GT1-1 hypothalamic neuronal cells: Action of protein kinase C. Neuroreport. 8(16):3541-6.

53. Jeong SJ, Kim K, Suh YH. (1997). Age-related changes in the expression of Alzheimer’s beta amyloid precursor protein (APP) in the brain of senescence accelerated mouse (SAM) p/10. Neuroreport. 8(7):1733-1737.

52. Sun W, Jarry H, Wuttke W, Kim K. (1997). Gonadotropin-releasing hormone (GnRH) modulates gamma aminobutyric acid-evoked intracellular calcium increase in immortalized hypothalamic GnRH neurons. Brain Research. 747(1):70-7.

51. Cho S, Han J, Sun W, Kwon HB, Jarry H, Wuttke W, Kim K. (1997). Evidence for autocrine inhibition of GnRH gene transcription by GnRH in hypothalamic GT1-1 neuronal cells. Mol. Brain Research. 50(1-2):51-58.



50. Chung YD, Kwon KC, Chung KW, Kim SJ, Kim K, Lee CC. (1996). Identification of ovarian enhancer-binding factors which bind to ovarian enhancer 1 of the Drosophila genes yp1 and yp2. Mol. Gen. Genet. 251(3):347-351.

49. Lee CS, Kim K, Yu DY, Lee KK. (1996). An efficient expression of human growth hormone (hGH) in the milk of transgenic mice using rat - casein/hGH fusion genes. Appl. Biochem. Biotechnol. 56(3):211-222.

48. Park D, Cheon M, Kim C, Kim K, Ryu K. (1996). Progesterone together with estradiol promotes luteinizing hormone beta-subunit mRNA stability in rat pituitary cells cultured in vitro. Eur. J. Endocrinol. 134(2):236-242.

47. Wuttke W, Jarry H, Feleder C, Moguilevsky J, Leonhardt S, Seong JY, Kim K. (1996). The neurochemistry of the GnRH pulse generator. Acta. Neurobiol. Exp. 56(3):707-713.

46. Seong JY, Kim K. (1996). Measurement of GnRH mRNA levels by Northern blot hybridization assay and competitive RT-PCR in the rat preoptic area. Neuroscience Protocols. 3:1-17.

45. Lee DK, Sun W, Rhee K, Thompson EA, Lee CC, Kim K. (1996). Regulation of the thymidine kinase gene expression during liver regeneration and uterine tissue proliferation. Transgenics 2(1):89-98.

44. Shim C, Kwon HB, Kim K. (1996). Differential expression of laminin chain-specific transcripts during mouse preimplantation embryo development. Mol. Reprod. Develop. 44(1):44-55.

43. Sun W, Lee DK, Lee CC, Kim K. (1996). Differential expression of D-type G1 cyclins during mouse development and liver regeneration in vivo. Mol. Reprod. Develop. 43(4):414-420.



42. Seong JY, Jarry H, Kuhnemuth S, Leonhardt S, Wuttke W, Kim K. (1995). Effect of GABAergic compounds on GnRH receptor gene expression in the rat. Endocrinology. 136(6):2587-2593.

41. Leonhardt S, Seong JY, Kim K, Thorun Y, Wuttke W, Jarry H. (1995). Activation of central GABAA- but not of GABAB-receptor causes a rapid reduction of GnRH gene expression in the preoptic/anterior hypothalamic area of ovariectomized rats. Neuroendocrinology. 61(6):655-662.

40. Kim DS, Yoon JH, Ahn SK, Kim KE, Seong RH, Hong SH, Kim K, Ryu K, Park SD. (1995).  A 33kDa Pit-1-like protein binds to the distal region of the human thyrotropin alpha-subunit gene. J. Mol. Endocrinol. 14(3):313-322.

39. Kang SH, Seong JY, Cho S, Cho H, Kim K. (1995). Acute increase in GABAergic neurotransmission exerts a stimulatory effect on GnRH gene expression in ovariectomized estrogen and progesterone treated adult female rats. Neuroendocrinology. 61(5):486-492.

38. Chung YD, Kwon HB, Chung KW, Kim SJ, Choe OM, Yong N, Kim K , Lee CC. (1995). Regulation of yolk protein 2 gene expression in Drosophila immigrans. Mol. Cells 5(4):325-329.

37. Kim J, Kim JY, Kim K, Yu MH. (1995). Isolation and characterization of the caprine genomic beta-lactoglobulin gene. Mol. Cells. 5:209-216.



36. Lee DK, Sun W, Rhee KS, Cho H, Lee CC, Kim K. (1994). Analysis of thymidine kinase gene expression in preimplantation mouse embryos. Mol. Reprod. Develop. 39(3):259-267.

35. Cho BN, Seong JY, Cho H, Kim K. (1994). Progesterone stimulates GnRH gene expression in the hypothalamus of ovariectomized, estrogen treated adult rats. Brain Research. 652(1):177-180.

34. Lee DK, Sun W, Lim C, Rhee K. Thompson EA, Lee CC, Cho WK, Kim K. (1994). Murine thymidine kinase in transgenic mice. Transgenics. 1: 337- 347.

33. Yoon M, Lee DK, Ryu K, Lee CC, Kim K. (1994). Effect of testosterone and its metabolites on LHRH and LH gene expression in castrated adult rats. Neuroendo. Lett. 16:97-102.

32. Yoon M, Seong JY, Song E, Ryu K, Kim K. (1994). Temporal changes in LHRH and LH subunit messenger RNA level in response to testosterone in castrated adult rats. Neuroendo. Lett. 16:89-95.

31. Lee BJ, Choi WS, Kim MO, Sun W., Seong JY, Kim K. (1994). Presence of gonadotropin-releasing hormone mRNA in the rat olfactory piriform cortex. Brain Research. 648(1):148-151.

30. Suh J, Song ES, Yu MH, Kim K. (1994). Cross-talk between N-methyl-D-asparate and adrenergic neurotransmission in the regulation of hypothalamic GnRH gene expression. Brain Research. 645(1-2):36-40.

29. Kim K, Lee BJ. Cho BN, Kang SS, Choi WS, Park SD, Lee CC, Cho WK, Wuttke W. (1994). A blockade of noradrenergic neurotransmission with diethyldithiocarbamic acid decreases mRNA level of gonadotropin releasing- hormone (GnRH) in the hypothalamus of ovariectomized, steroid-treated prepubertal rats. Neuroendocrinology. 59(6):539-544.

28. Lee SH, Choi WS, Kim C, Kang HM, Geum D, Park H-S, Park YM, Lee CC, Kim K. (1994). A local regulation of GnRH release and gene expression in rat granulosa cells by endogenous opioid peptide and GnRH analogues. Mol. Cells. 4:473-479.

27. Choi WS, Lee SH, Yu SK, Baik SH, Lee CC, Kim K. (1994). Expression and cellular localization of gonadotropin releasing hormone in the rat gonad. Mol. Cells. 4:267-272.

26. Lee SH, Song E, Yu SK, Kim C, Lee DK, Choi WS and Kim K. (1994). Temporal changes in ovarian gonadotropin-releasing hormone mRNA levels by gonadotropins in the rat. Mol. Cells. 4:39-44.



25. Kim K, Jarry H, Knoke I, Seong JY, Leonhardt S, Wuttke W. (1993). Competitive PCR for quantitation of GnRH mRNA level in a single micropunch of the rat preoptic area. Mol. Cell. Endocrinol. 97(1-2):153-158.

24. Kwon HB, Ahn RS, Lee WK, Im WB, Lee CC, Kim K. (1993). Changes in the activities of steroidogenic enzymes during the development of ovarian follicles in Rana nigromaculata. Gen. Com. Endocrinol. 92(2):225-232.

23. Seong JY, Lee YK, Lee CC, Kim K. (1993). NMDA receptor antagonist decreases the progesterone-induced increase in GnRH gene expression in the rat hypothalamus. Neuroendocrinology. 58(2):234-239.

22. Kim K, Lim IS, Cho BN, Kang SS, Lee BJ, Choi KH, Chung CH, Lee CC, Cho WK, Wuttke W. (1993). A partial blackade of catecholaminergic neurotransmission with 6-hydroxydopamine decreases mRNA level of gonadotropin releasing hormone in the male rat hypothalamus. Neuroendocrinology. 58(1):146-152.

21. Cho BN, Suh YH, Yoon YD, Lee CC, Kim K. (1993). Progesterone inhibits the estrogen-induced prolactin gene expression in the rat pituitary. Mol. Cell. Endocrinol. 93(1):47-52.



20. Pak JW, Chung KW, Lee CC, Kim K, Namkoog Y, Koolman J. (1992). Evidence for multiple forms of the prothoracicotropic hormone in Drosophila melanogaster and indication of a new function. J. Insect Physiol. 38(3):167-176.

19. Shim C, Lee DK, Lee CC, Cho WK, Kim K. (1992). Inhibitory effect of purines in meiotic maturation of denuded mouse oocytes. Mol. Reprod. Develop. 31(4): 280-286.

18. Choi H, Kim K, Choi K. (1992). Effect of nicotine on the regulation of tyrosine hydroxylase gene expression in PC12 cells. Mol. Cells. 1:421-424.



17. Kim K, Lee BJ, Lee CC, Cho WK, Ramirez VD. (1991). Adrenergic mediation of the naloxone-induced GnRH release from hypothalami of ovariectomized, steroid-treated immature rats. Acta. Endocrinol. 125(5):680-686.

16. Seol JH, Woo SK, Jung EM, Yoo SJ, Lee CS, Kim K, Tanaka K, Ichihara A, Ha DB, Chung CH. (1991). Protease Do is essential for survival of Escherichia coli at high temperature: Its identity with the htrA gene product. Biochem. Biophys. Res. Commun. 176(2):730-736.

15. Kang HM, Cho C, Lee KK, Kwon HB, Kim K, Cho WK. (1991). Protein modification by phosphorylation during the process of nuclear membrane dissolution in puromycin-treated mouse oocytes. Biol. Reprod. 44(4):590-598.

14. Baik SH, Choi YS, Ahn H, Kim K, Lee CC, Cho WK. (1991). Effects of estrogen and dopamine on prolactin synthesis in the rat pituitary: Immunohistochemistry and in situ hybridization. Mol. Cells 1:307-315.

13. Park KS, Cho CH, Lee KK, Kim K, Lee CC, Cho WK. (1991). Temporal relationship between histone H1 kinase activity and maturation promoting factor activity during mouse oocyte maturation. Mol. Cells 1:197-201.



12. Kang HM, Kim K, Kwon HB, Cho WK (1990). Regulation of laminin gene expression in the expansion of mouse blastocyst. Mol. Reprod. Develop. 27(3):191-199.

11. Lee BJ, Kim K, Cho WK. (1990). Activation of intracellular pathways with forskolin and phorbol ester increases LHRH mRNA level in the rat hypothalamus superfused in vitro. Mol. Brain Research. 8(3):185-191.



10. Kim K, Lee BJ, Park Y, Cho WK. (1989). Progesterone increases messenger ribonucleic acid (mRNA) encoding luteinizing hormone releasing hormone (LHRH) level in the hypothalamus of ovariectomized estradiol-primed prepubertal rats. Mol. Brain Research. 6(2-3):151-158.

9. Kim J, Kim HK, Kim K, Kim SR, Cho WK. (1989). Multiple forms of alkaline phosphatase in mouse preimplantation embryos. J. Reprod. Fertil. 86(1):65-72.



8. Kim K, Lee CS, Cho WK, Ramirez VD. (1988). Effect of chronic administration of progesterone on the naloxone-induced LHRH release from hypothalami of ovariectomized, estradiol-primed prepubertal rats. Life Sciences. 43(7):609-613.

7. Park Y, Park SD, Cho WK, Kim K. (1988). Testosterone stimulates LH-RH-like mRNA level in the rat hypothalamus. Brain Research. 451(1-2):255-260.



6. Kim K, Ramirez VD. (1986). In vitro LHRH release as a function of the rat estrous cycle: The effect of progesterone. Neuroendocrinology. 42(5):392-398.

5. Kim K, Ramirez VD. (1986). Effects of prostaglandin E2, forskolin and cholera toxin on cyclic AMP production and in vitro LHRH release from the rat hypothalamus. Brain Research. 386(1-2):258-265.



4. Ramirez VD, Kim K, Dluzen D. (1985). Progesterone action on the LHRH and the nigrostriatal dopamine neuronal systems: In vitro and in vivo studies. Recent Prog. Horm. Res. 42:421-472.

3. Kim K, Ramirez VD. (1985). Dibutyryl cyclic adenosine monophosphate stimulates in vitro luteinizing hormone-releasing hormone release only from median eminence derived from ovariectomized, estradiol-primed rats. Brain Research. 342(1):154-157.

2. Kim K, Ramirez VD. (1985). In vitro luteinizing hormone releasing hormone (LHRH) release from superfused rat hypothalami: Site of action of progesterone and effect of estrogen. Endocrinology. 116(1): 252-258.



1. Kim K, Ramirez VD. (1982). In vitro progesterone stimulates the release of luteinizing hormone releasing hormone (LHRH) from superfused hypothalamic tissue from ovariectomized, estradiol-primed prepubertal rats. Endocrinology. 111:750-756.